33469-16-8 Usage
Uses
Used in Pharmaceutical Industry:
1H-Imidazole, 2-(3,4-dichlorophenyl)-5-(trifluoromethyl)-, is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicine and healthcare.
Used in Agrochemical Industry:
In the agrochemical sector, 1H-Imidazole, 2-(3,4-dichlorophenyl)-5-(trifluoromethyl)-, serves as a crucial component in the creation of agrochemicals. Its incorporation into these products enhances their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Biochemical Research and Analysis:
1H-Imidazole, 2-(3,4-dichlorophenyl)-5-(trifluoromethyl)-, is employed as a valuable tool in biochemical research and analysis. Its distinctive properties make it suitable for studying various biological processes and interactions, thereby aiding in the understanding of complex biological systems and the development of novel therapeutic strategies.
Used in the Development of New Drugs:
This chemical compound is also used in the development of new drugs, where its unique structure and properties can be leveraged to design and synthesize innovative pharmaceutical agents with improved efficacy and selectivity. Its potential in drug discovery makes it an essential component in the ongoing pursuit of novel therapeutic solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 33469-16-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,4,6 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 33469-16:
(7*3)+(6*3)+(5*4)+(4*6)+(3*9)+(2*1)+(1*6)=118
118 % 10 = 8
So 33469-16-8 is a valid CAS Registry Number.
33469-16-8Relevant academic research and scientific papers
Trifluoromethylimidazoles and a method for their preparation
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, (2008/06/13)
4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammoni
2-Pyrazinyl-trifluoromethylimidazoles and a method for their preparation
-
, (2008/06/13)
4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammoni
4-Trifluoromethylimidazoles and 5-(4-pyridyl)-1,2,4-triazoles, new classes of xanthine oxidase inhibitors.
Baldwin et al.
, p. 895,896 (2007/10/04)
The syntheses of a number of 2-substituted 4-trifluoromethylimidazoles and 3-substituted 5-(4-pyridyl)-1,2,4-triazoles are described. The trifluoromethylimidazoles were prepared from 3,3-dibromo-1,1,1-trifluoroacetone after hydrolysis with aqueous sodium acetate solution and condensation with an aldehyde in the presence of ammonia. Basic hydrolysis of the trifluoromethyl group was found to provide a facile method for the synthesis of imidazole-4-carboxylic acids. In the imidazole series a 2-aryl substituent and a free imino group were required for xanthine oxidase inhibitory activity. The triazoles were obtained through the reaction of an aroylhydrazine and an imino ether followed by thermal ring closure of the intermediate acylamidrazone. As in the imidazole series, a free imino group is an absolute requirement for in vitro activity. Additional structure-activity relationships of these compounds are presented.
