Welcome to LookChem.com Sign In|Join Free

CAS

  • or

33469-18-0

2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole is a chemical compound characterized by an imidazole ring structure, a trifluoromethyl group, and a 4-methylphenyl ring. The imidazole ring is a five-membered planar ring with two nitrogen atoms, while the trifluoromethyl group contributes to the compound's reactivity due to the highly electronegative fluorine atoms. The 4-methylphenyl, or para-tolyl group, is a phenyl derivative with a methyl group attached to the fourth carbon atom. This complex structure endows the compound with intriguing chemical properties, making it a valuable subject for scientific research and development.

33469-18-0 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 33469-18-0 Structure

  • Basic information

    1. Product Name: 2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole
    2. Synonyms: 2-p-tolyl-4-(trifluoromethyl)-1H-imidazole;2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole;1H-IMidazole, 2-(4-Methylphenyl)-5-(trifluoroMethyl)-;2-(4-methylphenyl)-5-(trifluoromethyl)-1H-Imidazole
    3. CAS NO:33469-18-0
    4. Molecular Formula: C11H9F3N2
    5. Molecular Weight: 226.2
    6. EINECS: N/A
    7. Product Categories: Heterocycle
    8. Mol File: 33469-18-0.mol

  • Chemical Properties

    1. Melting Point: 221-222 °C
    2. Boiling Point: 345.391 °C at 760 mmHg
    3. Flash Point: 162.687 °C
    4. Appearance: /
    5. Density: 1.284
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.516
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 10.79±0.10(Predicted)
    11. CAS DataBase Reference: 2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole(33469-18-0)
    13. EPA Substance Registry System: 2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole(33469-18-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 33469-18-0(Hazardous Substances Data)

33469-18-0 Usage

Uses

Used in Pharmaceutical Research:
2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential applications in treating a range of diseases.
Used in Chemical Synthesis:
In the field of organic chemistry, 2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole serves as a versatile building block for the creation of more complex molecules. Its reactivity, stemming from the trifluoromethyl group and the imidazole ring, enables the formation of a wide array of chemical products.
Used in Material Science:
2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole is employed as a component in the development of advanced materials, such as polymers and coatings, that exhibit specific properties like enhanced stability, chemical resistance, or unique optical characteristics.
Used in Agrochemical Development:
In the agrochemical industry, 2-(4-Methylphenyl)-4-(trifluoromethyl)-1H-imidazole is used as a starting material for the synthesis of novel pesticides and herbicides. Its chemical structure provides a foundation for the design of more effective and environmentally friendly agrochemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 33469-18-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,4,6 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 33469-18:
(7*3)+(6*3)+(5*4)+(4*6)+(3*9)+(2*1)+(1*8)=120
120 % 10 = 0
So 33469-18-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H9F3N2/c1-7-2-4-8(5-3-7)10-15-6-9(16-10)11(12,13)14/h2-6H,1H3,(H,15,16)

33469-18-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-Methylphenyl)-5-(trifluoromethyl)-1H-imidazole

1.2 Other means of identification

Product number -
Other names PC5748

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33469-18-0 SDS

33469-18-0Relevant articles and documents

Discovery of novel 2-aryl-4-bis-amide imidazoles (ABAI) as anti-inflammatory agents for the treatment of inflammatory bowel diseases (IBD)

Li, Ling,Yuan, Sijie,Lin, Lin,Yang, Fang,Liu, Ting,Xu, Chenglong,Zhao, Huiting,Chen, Jingxuan,Kuang, Peihua,Chen, Ting,Liao, Wenzhen,Chen, Jianjun

, (2022/01/28)

A series of 2-Aryl-4-Bis-amide Imidazoles (ABAI-1 to 30) were designed as anti-inflammatory agents. These compounds were synthesized and evaluated for the in vitro anti-inflammatory activities (inhibition of NO production and release of inflammatory cytok

3-dimethylhydrazono-1,1,1-trifluoro-2-propanone as a useful synthetic equivalent of trifluoropyruvaldehydeapplication to synthesis of fluorine-containing heterocycles

Kamitori, Yasuhiro

, p. 1185 - 1190 (2007/10/03)

3-Dimethylhydrazono-1,1,1-trifluoro-2-propanone (4) which is easily obtainable from formaldehyde dimethylhydrazone and trifluoroacetic anhydride was found to be an usuful synthetic equivalent of trifluoropyruvaldehyde for the synthesis of fluorine-containing heterocycles. With the use of 4, 4-trifluoromethylimidazoles and 2-trifluoromethylquinoxaline were successfully synthesized.

Synthesis, structure, and neuroprotective properties of novel imidazolyl nitrones

Dhainaut, Alain,Tizot, André,Raimbaud, Eric,Lockhart, Brian,Lestage, Pierre,Goldstein, Solo

, p. 2165 - 2175 (2007/10/03)

A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This connectivi

Trifluoromethylimidazoles and a method for their preparation

-

, (2008/06/13)

4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammoni

2-Pyrazinyl-trifluoromethylimidazoles and a method for their preparation

-

, (2008/06/13)

4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammoni

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 33469-18-0