3349-63-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Indanone oxime is used as a synthetic intermediate for the preparation of 2-aminoindane hydrochloride, which is an essential compound in the pharmaceutical industry. The conversion is achieved through a reduction process using an active palladium catalyst, which plays a crucial role in facilitating the reaction.
General Description:
The reduction of 2-indanone oxime to 2-aminoindane has been reported in the literature, highlighting its significance as a synthetic intermediate. This transformation is of particular interest due to the potential applications of 2-aminoindane and its derivatives in various fields, including the development of new drugs and pharmaceutical compounds.

InChI:InChI=1/C9H9NO/c11-10-9-5-7-3-1-2-4-8(7)6-9/h1-4,11H,5-6H2

Upstream product

• 7803-49-8 hydroxylamine 
• 615-13-4 2-indanone 
• 10368-44-2 trans-2-bromo-1-indanol 
• 103324-09-0 2-methoxy-2,3-dihydro-1H-inden-1-ol 

Downstream Products

• 2975-41-9 2,3-dihydro-1H-inden-2-amine 
• 2338-18-3 2-aminoindane hydrochloride 
• 615-13-4 2-indanone 
• 1236106-49-2 2-(4-methoxyphenyl)-1',3'-dihydrospiro[1,3,2-dithiaphosphetane-4,2'-indene]2-sulfide 
• 177-52-6 Trithio-indan-2-on 
• 115679-50-0 di(2-indenyl) sulfide 
• 1236106-57-2 2-(phenylsulfonyl)-1',3'-dihydrospiro[1,3,2-dithiaphosphetane-4,2'-indene]2-sulfide 
• 66865-49-4 E,Z-1-benzyl-2-indanone oxime-o-methyl ether 

Relevant academic research and scientific papers

Substituted ring compound and its method and use thereof

The invention provides a substituted cyclic compound as well as a use method and application thereof. The compound is a compound as shown in a formula (I) or stereoisomers, stereomers, tautomers, nitric oxides, solvates, metabolites and pharmaceutically acceptable salts or prodrugs of the compound as shown in the formula (I). The invention further provides a medicament composition containing the compound. The compound and the medicament composition are capable of regulating the activity of protein kinase in a biological sample body and are used for protecting, treating or relieving proliferative diseases of patients. The formula (I) is as shown in the specification.

SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted alkynyl compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.