335087-47-3

Basic information

• Product Name: 8-{3-[4-(2-methoxy-5-trifluoromethylphenyl)-1-piperazinyl]-propylcarbamoyl}-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran
• CAS NO: 335087-47-3
• Molecular Weight: 579.619
• Mol File: 335087-47-3.mol

Chemical Properties

• CAS DataBase Reference: 8-{3-[4-(2-methoxy-5-trifluoromethylphenyl)-1-piperazinyl]-propylcarbamoyl}-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 8-{3-[4-(2-methoxy-5-trifluoromethylphenyl)-1-piperazinyl]-propylcarbamoyl}-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran(335087-47-3)
• EPA Substance Registry System: 8-{3-[4-(2-methoxy-5-trifluoromethylphenyl)-1-piperazinyl]-propylcarbamoyl}-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran(335087-47-3)

Safety Data

• Hazardous Substances Data: 335087-47-3(Hazardous Substances Data)

Upstream product

• 178974-29-3 4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazine 
• 335087-42-8 8-<3-{4-[2-(2,2,2-trifluoroethoxy)-phenyl]-1-piperazinyl}propylcarbamoyl>-3-methyl-4-oxo-2-phenyl-4H-1-benzopyran 

Relevant articles and documents

BENZOPYRAN DERIVATIVES

Benzopyran derivatives (I) (R = phenyl, alkoxycarbonyl, alkylcarbonyl, CONH2, CONH(alkyl), CON(alkyl)2, CN or alkoxycarbonylamino; R2 = alkyl, alkoxy, polyfluoroalkoxy, OH or CF3SO2O; each of R4 and R5 independently = H, halogen, polyfluoroalkyl, polyfluo

Benzopyran derivatives

The invention relates to novel benzopyran derivatives of formula I, their N-oxides and pharmaceutically acceptable salts thereof. The compounds are endowed with enhanced selectivity for alpha1-adrenergic receptors and a low activity in lowering blood pressure. The compounds are useful in the treatment of obstructive syndromes of the lower urinary tract, including benign prostatic hyperplasia (BPH), and in the treatment of lower urinary tract symptoms (LUTS), neurogenic lower urinary tract dysfunction (NLUTD), and other conditions.