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1H-Imidazole, 2-(2,4-dichlorophenyl)-5-(trifluoromethyl)is a chemical compound with the molecular formula C9H5Cl2F3N2. It is a derivative of imidazole, a heterocyclic organic compound, featuring a trifluoromethyl group and two dichlorophenyl groups. This versatile chemical is known for its diverse biological activities and is utilized in various industries, such as pharmaceuticals and agrochemicals, for its potential anti-fungal, anti-cancer, and anti-inflammatory properties. Furthermore, it serves as a building block in the synthesis of other complex organic compounds. Careful handling is advised due to potential hazards, and appropriate precautions should be taken in laboratory or industrial settings.

33512-98-0

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33512-98-0 Usage

Uses

Used in Pharmaceutical Industry:
1H-Imidazole, 2-(2,4-dichlorophenyl)-5-(trifluoromethyl)is used as a pharmaceutical agent for its potential anti-fungal, anti-cancer, and anti-inflammatory properties. Its diverse biological activities make it a promising candidate for the development of new drugs to treat various diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical industry, 1H-Imidazole, 2-(2,4-dichlorophenyl)-5-(trifluoromethyl)is used as a bioactive compound for its potential applications in pest control and crop protection. Its anti-fungal properties can be harnessed to develop effective fungicides to safeguard crops from fungal infections.
Used in Organic Synthesis:
1H-Imidazole, 2-(2,4-dichlorophenyl)-5-(trifluoromethyl)is used as a building block in the synthesis of complex organic compounds. Its unique structure and functional groups make it a valuable component in the creation of new molecules with specific properties and applications in various fields, including materials science, medicinal chemistry, and chemical research.

Check Digit Verification of cas no

The CAS Registry Mumber 33512-98-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,5,1 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 33512-98:
(7*3)+(6*3)+(5*5)+(4*1)+(3*2)+(2*9)+(1*8)=100
100 % 10 = 0
So 33512-98-0 is a valid CAS Registry Number.

33512-98-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,4-dichloro-phenyl)-4-trifluoromethyl-1(3)H-imidazole

1.2 Other means of identification

Product number -
Other names 2-(2,4-Dichloro-phenyl)-4-trifluoromethyl-1H-imidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33512-98-0 SDS

33512-98-0Relevant academic research and scientific papers

Discovery of novel 2-aryl-4-bis-amide imidazoles (ABAI) as anti-inflammatory agents for the treatment of inflammatory bowel diseases (IBD)

Li, Ling,Yuan, Sijie,Lin, Lin,Yang, Fang,Liu, Ting,Xu, Chenglong,Zhao, Huiting,Chen, Jingxuan,Kuang, Peihua,Chen, Ting,Liao, Wenzhen,Chen, Jianjun

, (2022/01/28)

A series of 2-Aryl-4-Bis-amide Imidazoles (ABAI-1 to 30) were designed as anti-inflammatory agents. These compounds were synthesized and evaluated for the in vitro anti-inflammatory activities (inhibition of NO production and release of inflammatory cytok

Trifluoromethylimidazoles and a method for their preparation

-

, (2008/06/13)

4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammoni

2-Pyrazinyl-trifluoromethylimidazoles and a method for their preparation

-

, (2008/06/13)

4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammoni

4-Trifluoromethylimidazoles and 5-(4-pyridyl)-1,2,4-triazoles, new classes of xanthine oxidase inhibitors.

Baldwin et al.

, p. 895,896 (2007/10/04)

The syntheses of a number of 2-substituted 4-trifluoromethylimidazoles and 3-substituted 5-(4-pyridyl)-1,2,4-triazoles are described. The trifluoromethylimidazoles were prepared from 3,3-dibromo-1,1,1-trifluoroacetone after hydrolysis with aqueous sodium acetate solution and condensation with an aldehyde in the presence of ammonia. Basic hydrolysis of the trifluoromethyl group was found to provide a facile method for the synthesis of imidazole-4-carboxylic acids. In the imidazole series a 2-aryl substituent and a free imino group were required for xanthine oxidase inhibitory activity. The triazoles were obtained through the reaction of an aroylhydrazine and an imino ether followed by thermal ring closure of the intermediate acylamidrazone. As in the imidazole series, a free imino group is an absolute requirement for in vitro activity. Additional structure-activity relationships of these compounds are presented.

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