335159-97-2

Upstream product

• 188899-14-1 (3S,4E)-3-(tert-butyldimethylsilyloxy)-4-methyl-5-(2-methyl-1,3-thiazol-4-yl)pent-4-en-1-ol 
• 335159-93-8 4-(3-(tert-butyl-dimethyl-silanyloxy)-5-{3-[3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-propyl]-phenyl}-2-methyl-pent-1-enyl)-2-methyl-thiazole 
• 848487-38-7 4-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-5-(2-nitro-phenylselanyl)-pent-1-enyl]-2-methyl-thiazole 
• 267877-84-9 4-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-penta-1,4-dienyl]-2-methyl-thiazole 

Downstream Products

• 335159-99-4 (3S,6R,7S,8S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-9-{3-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-5-(2-methyl-thiazol-4-yl)-pent-4-enyl]-phenyl}-4,4,6,8-tetramethyl-5-oxo-nonanoic acid 
• 335160-01-5 (3S,6R,7S,8S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-9-{3-[(E)-(S)-3-hydroxy-4-methyl-5-(2-methyl-thiazol-4-yl)-pent-4-enyl]-phenyl}-4,4,6,8-tetramethyl-5-oxo-nonanoic acid 

Relevant academic research and scientific papers

Epothilones and their analogs -potential new weapons in the fight against cancer

Epothilones are a new class of microtubule depolymerization inhibitors, which inhibit the growth of a broad range of human cancer cell lines in vitro with low nM or sub-nM IC50s. Unlike many other cytotoxic anticancer agents epothilones are also active in