335160-69-5

Basic information

• Product Name: (S)-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-5-(2-hydroxyethyl)-2-piperazinone
• Synonyms: (S)-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-5-(2-hydroxyethyl)-2-piperazinone
• CAS NO: 335160-69-5
• Molecular Weight: 394.468
• Mol File: 335160-69-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-5-(2-hydroxyethyl)-2-piperazinone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-5-(2-hydroxyethyl)-2-piperazinone(335160-69-5)
• EPA Substance Registry System: (S)-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-5-(2-hydroxyethyl)-2-piperazinone(335160-69-5)

Safety Data

• Hazardous Substances Data: 335160-69-5(Hazardous Substances Data)

Upstream product

• 335160-63-9 (1S)-tert-butyl-1-{[(chloroacetyl)(2,4-dimethoxybenzyl)amino]-methyl}but-3-enylcarbamate 
• 335160-65-1 (S)-5-allyl-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-2-piperazinone 
• 335160-61-7 (1S)-tert-butyl-1-{[(2,4-dimethoxybenzyl)amino]methyl}but-3-enylcarbamate 
• 208521-14-6 (S)-2-[N²-[(tert-butyloxy)carbonyl]amino]-N-methoxy-N-methyl-4-penteneamide 
• 90600-20-7 (2S)-2-[(tert-butoxycarbonyl)amino]pent-4-enoic acid 
• 95107-99-6 tert-butyl (S)-(1-oxopent-4-en-2-yl)carbamate 
• 20781-21-9 2,4-dimethoxybenzylamine hydrochloride 
• 335160-67-3 (S)-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-5-(2-oxoethyl)-2-piperazinone 

Downstream Products

• 335160-73-1 1(R),5(S)-8-tert-butoxycarbonyl-3-(2,4-dimethoxybenzyl)-3,8-diaza-2-oxobicyclo[3.2.1]octane 
• 335160-71-9 (S)-4-tert-butoxycarbonyl-1-(2,4-dimethoxybenzyl)-5-[2-(phenylsulfonyloxy)ethyl]-2-piperazinone 

Relevant articles and documents

3,8-Diazabicyclo[3.2.1]octan-2-one peptide mimetics: synthesis of a conformationally restricted inhibitor of farnesyltransferase.

A new synthesis of the 3,8-diazabicyclo[3.2.1]octan-2-one framework is described. Transannular enolate alkylation of piperazinone derivatives provides a flexible route to highly constrained bicyclic peptidomimetic synthons with substitution at the Calpha