33520-96-6

Usage

Uses

Used in Pharmaceutical Research:
1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-oxo-1,2-dihydroisoquinolinium is used as a research compound for exploring its potential biological activities and applications in the development of new pharmaceutical agents. Its unique structure may contribute to its interaction with biological targets, making it a promising candidate for further investigation in drug discovery processes.
Used in Drug Discovery:
In the field of drug discovery, 1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-oxo-1,2-dihydroisoquinolinium is utilized as a starting point for the synthesis of novel compounds with potential therapeutic effects. Its structural features may be optimized to enhance its pharmacological properties, leading to the development of new drugs with improved efficacy and safety profiles.
Note: Since the provided materials do not specify particular applications or industries for 1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-oxo-1,2-dihydroisoquinolinium, the uses listed above are general and based on the potential of the compound's structure and class. Further research and development would be necessary to identify specific applications and industries where 1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-oxo-1,2-dihydroisoquinolinium could be effectively utilized.

Upstream product

• 58-74-2 Papaverine 
• 61-25-6 papaverine hydrochloride 

Downstream Products

• 1374461-35-4 N-methoxy 1-(3,4-dimethoxybenzyl)-6,7-dimethoxyisoquinolinium perchlorate 
• 1374461-41-2 C₂₁H₂₃NO₅ 
• 58-74-2 Papaverine 
• 73841-84-6 1,2-dihydropapaverine 
• 40360-96-1 2-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-benzo[f][1,3]oxazepine 

Relevant academic research and scientific papers

Oxidation and degradation products of papaverine, Part II[1]: Investigations on the photochemical degradation of papaverine solutions

The structure of the final degradation product formed in papaverine solutions in either water or chloroform was found to be a 2,3,9,10-tetramethoxy-12-oxo-12H-indolo[2,1-a]isoquinolinylium salt (a dibenzo[b,g]pyrrocolonium derivative). Its formation from

Natural Product Diversification by One-Step Biocatalysis using Human P450 3A4

Efficient synthetic techniques for the diversification of natural products are incremental for drug discovery processes of the pharmaceutical industry because these complex bioactive compounds often require an adjustment of properties. Human liver P450 3A4, key player of the body's detoxification system and decisive factor of a drug's metabolic fate, is renowned for its broad substrate scope including many natural products. In this study, we investigated the synthetic potential of human P450 3A4 for the diversification of natural product classes and isolated the produced metabolites of six selected natural products at a preparative 100-mg scale. Aided by efficient expression levels in P. pastoris, this whole-cell biocatalyst was found to be highly effective at the intended job allowing the identification of a total of 31 authentic human metabolites, many of them for the first time. By revealing an unprecedented degree of diversification, this study extends the synthetic repertoire for efficient enzymatic natural product modification in a one-step fashion and adds a completely new view to an old enzyme traditionally used for inhibition and toxicology studies.

Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a

The metabolism of papaverine, the opium benzylisoquinoline alkaloid, with Aspergillus niger NRRL 322, Beauveria bassiana NRRL 22864, Cunninghamella echinulate ATCC 18968 and Cunninghamella echinulate ATCC 1382 has resulted in O-demethylation, O-methylgluc

Formation of the N-oxides of heteroaromatic nitrogen compounds by perfluorinated oxaziridines

On treatment with perfluoro-cis-2,3-dialkyloxaziridines, mono-, bi-, and tricyclic nitrogen heteroaromatics afford the corresponding N-oxides under mild reaction conditions and in medium to high yields. The course of the reaction is not altered by the presence of various residues on the ring or in side chains and the N-oxides of polyfunctional, naturally occurring compounds have been prepared.