33524-71-9

Upstream product

• 64591-47-5 2-methoxy-1-(4-methylphenyl)ethan-1-one 
• 886-38-4 diphenylcyclopropenone 
• 874-60-2 4-methyl-benzoyl chloride 
• 102-04-5 1,3-Diphenylpropanone 
• 103-82-2 phenylacetic acid 

Relevant academic research and scientific papers

Catalytic [3+3] Annulation of β-Ketoethers and Cyclopropenones via C(sp3)—O/C—C Bond Cleavage under Transition-Metal Free Conditions

The efficient cleavage of carbon-oxygen (C—O) bond is highly important for the transformation of oxygen-rich biomass and industry chemicals. Herein, an efficient [3+3] annulation of β-ketoethers with cyclopropenones in the presence of catalytic base has b

Synthesis method of 2-pyrone compound and alpha, beta-unsaturated chain ester compound

The invention provides a synthesis method of a 2-pyrone compound 3 and an alpha, beta-unsaturated chain ester compound 4, and belongs to the technical field of organic synthesis. According to the synthesis method, lignin and cyclopropenone are catalyzed by potassium tert-butoxide to be subjected to [3 + 3] cycloaddition reaction to prepare the 2-pyrone compound. In an organic solvent, potassium tert-butoxide is used as a catalyst, and the lignin compound 1 and the cyclopropenone compound 2 react under a heating condition to obtain a 2-pyrone compound 3; when R is aryl, alpha, beta unsaturated chain ester compounds 4 are also generated; according to the method, the beta-O-4 bond in the lignin model is selectively broken to synthesize the 2-pyrone compound; the used raw materials are simple and easy to obtain, the adopted catalyst is low in price, wide in source, easy to obtain and small in dosage, the reaction conditions are relatively mild, and the product can be obtained at a relatively high yield.

Rh(III)-Catalyzed [3 + 3] Annulation Reaction of Cyclopropenones and Sulfoxonium Ylides toward Trisubstituted 2-Pyrones

A new Rh(III)-catalyzed [3 + 3] annulation reaction between cyclopropenones and β-ketosulfoxonium ylides has been reported, enabling metal carbene insertion to access a wide range of trisubstituted 2-pyrones with moderate to excellent yields via C-C single-bond cleavage, in which sulfoxonium ylides serve as potential safe precursors of metal carbenes. This reaction occurred under redox-neutral conditions with a broad substrate scope.

Novel method for synthesizing 2H-pyran-2-one derivative through base catalysis

The invention discloses a novel method for synthesizing a 2H-pyran-2-one derivative through base catalysis. The method comprises the following steps: with 1,2-dichloroethane as a solvent and sulfur ylide as a nucleophilic reagent, carrying out alkaline ca