335293-17-9

Upstream product

• 335293-22-6 dimethyl 6-N-acetylamino-4-chloro-1,3-isophthalate 
• 335293-21-5 methyl 2-N-acetylamino-4-chloro-5-iodobenzoate 
• 335293-15-7 dimethyl 6-amino-4-chloro-1,3-isophthalate 
• 335293-23-7 3,4,5-trimethylphenylacetyl chloride 
• 199850-56-1 methyl 2-amino-4-chloro-5-iodobenzoate 
• 51719-67-6 3,4,5-trimethylphenylacetic acid 
• 5900-58-3 2-amino-4-chloro-benzoic acid methyl ester 
• 362604-16-8 dimethyl 6-N-(3,4,5-trimethylphenyl)acetylamino-4-chloro-1,3-isophthalate 

Downstream Products

• 335293-20-4 4-(2-(N-tert-butoxycarbonylazetidin-2(S)-yl)ethoxy)-7-chloro-2-oxo-3-(3,4,5-trimethylphenyl)-1,2-dihydroquinoline-6-carboxylic acid pyrimidin-4-ylamide 
• 808172-48-7 7-Chloro-4-[2-((R)-4-oxo-azetidin-2-yl)-ethoxy]-3-(3,4,5-trimethyl-phenyl)-2-(2-trimethylsilanyl-ethoxy)-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide 
• 362604-27-1 7-chloro-3-(3,4,5-trimethyl-phenyl)-2,4-bis-(2-trimethylsilanyl-ethoxy)-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide 
• 362604-25-9 7-chloro-3-(3,4,5-trimethyl-phenyl)-2,4-bis-(2-trimethylsilanyl-ethoxy)-quinoline-6-carboxylic acid 
• 808172-45-4 7-chloro-4-hydroxy-3-(3,4,5-trimethyl-phenyl)-2-(2-trimethylsilanyl-ethoxy)-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide 
• 808172-34-1 7-chloro-2-oxo-3-(3,4,5-trimethyl-phenyl)-4-(2-trimethylsilanyl-ethoxy)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide 

Relevant academic research and scientific papers

A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor

Extensive development of the structure - activity relationships of a screening lead determined three important pharmacophores for gonadotropin-releasing hormone (GnRH) receptor antagonist activity. Incorporation of the 3,4,5-trimethylphenyl group at the 3