335299-08-6Relevant academic research and scientific papers
Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents
Li, Zhili,Fennie, Michael W.,Ganem, Bruce,Hancock, Matthew T.,Kobaslija, Muris,Rattendi, Donna,Bacchi, Cyrus J.,O'Sullivan, Mary C.
, p. 251 - 254 (2001)
Several N-(3-phenylpropyl)-substituted spermidine and spermine derivatives were prepared and found to be potent competitive inhibitors of Trypanosoma cruzi trypanothione reductase (seven compounds with Ki values 5 μM are described). The most e
