Guanylyl-(3'->5')-guanosine, also known as cyclic guanosine monophosphate (cGMP), is a cyclic nucleotide that plays a crucial role in various cellular processes. It is synthesized from guanosine triphosphate (GTP) by the action of guanylate cyclase enzymes and serves as a second messenger in signal transduction pathways. cGMP is involved in the regulation of smooth muscle contraction, vasodilation, and the immune response. It is also implicated in the process of long-term potentiation, which is associated with learning and memory. The balance between cGMP and its counterpart, cyclic adenosine monophosphate (cAMP), is essential for maintaining proper cellular function. Dysregulation of cGMP levels can lead to various diseases, including cardiovascular and neurological disorders.
The CAS Registry Mumber 3353-33-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,5 and 3 respectively; the second part has 2 digits, 3 and 3 respectively. Calculate Digit Verification of CAS Registry Number 3353-33: (6*3)+(5*3)+(4*5)+(3*3)+(2*3)+(1*3)=71 71 % 10 = 1 So 3353-33-1 is a valid CAS Registry Number.