33537-97-2

Basic information

• Product Name: 6-CHLORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE
• Synonyms: 6-CHLORO-1,2,3,4-TETRAHYDROISOQUINOLINE HCL;6-CHLORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE;7-Chloro-1,2,3,4-tetrahydroisoquinoline hydrochloride;6-Chhloro-1,2,3,4-tetrahydroisoquinoline hydrochloride;Isoquinoline,6-chloro-1,2,3,4-tetrahydro-,hydrochloride;7-chloro-1,2,3,4-tetrahydroisoquinoline HCl;6-chloro-1,2,3,4-tetrahydro-,hydrochloride
• CAS NO: 33537-97-2
• Molecular Formula: C₉H₁₀ClN*ClH
• Molecular Weight: 204.1
• Mol File: 33537-97-2.mol

Chemical Properties

• Boiling Point: 302.3 °C at 760 mmHg
• Flash Point: 136.6 °C
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 6-CHLORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE(33537-97-2)
• EPA Substance Registry System: 6-CHLORO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE(33537-97-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 33537-97-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-Chloro-1,2,3,4-tetrahydro-isoquinoline hydrochloride is used as an intermediate compound for the synthesis of various pharmaceutical drugs. Its unique structure and reactivity make it a valuable building block in the development of new medications, particularly those targeting neurological disorders or pain management.
Used in Chemical Research:
In the field of chemical research, 6-chloro-1,2,3,4-tetrahydro-isoquinoline hydrochloride serves as a model compound for studying the properties and reactions of isoquinolines. Its multi-functionality allows researchers to explore its potential in various chemical transformations and to understand the underlying mechanisms of these reactions.
Used in Material Science:
6-Chloro-1,2,3,4-tetrahydro-isoquinoline hydrochloride is used as a component in the development of new materials with specific properties. Its incorporation into polymers or other materials can lead to the creation of novel compounds with enhanced characteristics, such as improved conductivity or increased stability.

InChI:InChI=1/C9H10ClN.ClH/c10-9-2-1-7-3-4-11-6-8(7)5-9;/h1-2,5,11H,3-4,6H2;1H

Downstream Products

• 1009344-42-6 N-[2-chloro-4-(6-chloro-3,4-dihydro-1H-isoquinolin-2-yl)-6-methyl-phenyl]-3,3-dimethylbutanamide 
• 1009344-32-4 N-[4-(6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)-2,6-dimethyl-phenyl]-3,3-dimethyl-butanamide 
• 1009344-30-2 N-[2-Chloro-4-(6-chloro-3,4-dihydro-1H-isoquinolin-2-yl)-6-trifluoromethyl-phenyl]-3,3-dimethyl-butanamide 

Relevant articles and documents

Method for preparing tetrahydroisoquinolines

A method for preparing 1,2,3,4-tetrahydroisoquinolines comprising heating N-halo or hydroxyethyl-N-benzylamines in an aluminum chloride melt at 160°-210°.