33543-79-2 Usage
General Description
1H-Imidazole-2-carboxylic acid, 1-methyl-, hydrazide (9CI) is a chemical compound with the molecular formula C5H8N4O. It is a derivative of imidazole, a five-membered heterocyclic aromatic ring containing two nitrogen atoms. 1H-Imidazole-2-carboxylicacid,1-methyl-,hydrazide(9CI) is commonly used in medicinal chemistry and pharmaceutical research as a building block for the synthesis of various compounds with potential biological activity. Its hydrazide group makes it a versatile intermediate for the preparation of various derivatives, leading to a wide range of potential applications in drug discovery and development. However, due to its potential reactivity and biological activity, proper handling and safety precautions should be observed when working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 33543-79-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,5,4 and 3 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 33543-79:
(7*3)+(6*3)+(5*5)+(4*4)+(3*3)+(2*7)+(1*9)=112
112 % 10 = 2
So 33543-79-2 is a valid CAS Registry Number.
33543-79-2Relevant articles and documents
5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS
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Page/Page column 83-84, (2010/11/17)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein A is hydrogen, C1-4alkyl, C3-6cycloalkyl, C1-3alkoxy, C1-3alkoxy C1-4alkyl, C1-2fluoroalkyl, halogen, NR6 R7, optionally substituted heteroaryl (Het), or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis, osteoarthritis or neurodegenerative disorders.
