33543-79-2 Usage
Uses
Used in Medicinal Chemistry:
1H-Imidazole-2-carboxylic acid, 1-methyl-, hydrazide (9CI) is utilized as a synthetic intermediate for the development of compounds with potential medicinal properties. Its hydrazide functionality allows for the creation of a wide range of derivatives, which can be explored for their therapeutic effects.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1H-Imidazole-2-carboxylic acid, 1-methyl-, hydrazide (9CI) is employed as a key component in the synthesis of new drug candidates. 1H-Imidazole-2-carboxylicacid,1-methyl-,hydrazide(9CI)'s reactivity and ability to form various derivatives make it a valuable asset in drug discovery, where it can be modified to target specific biological pathways or diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 33543-79-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,5,4 and 3 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 33543-79:
(7*3)+(6*3)+(5*5)+(4*4)+(3*3)+(2*7)+(1*9)=112
112 % 10 = 2
So 33543-79-2 is a valid CAS Registry Number.
33543-79-2Relevant academic research and scientific papers
5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS
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Page/Page column 83-84, (2010/11/17)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein A is hydrogen, C1-4alkyl, C3-6cycloalkyl, C1-3alkoxy, C1-3alkoxy C1-4alkyl, C1-2fluoroalkyl, halogen, NR6 R7, optionally substituted heteroaryl (Het), or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis, osteoarthritis or neurodegenerative disorders.
