33557-13-0

Upstream product

• 6167-32-4 1,6:3,4-dianhydro-2-O-tosyl-D-galactose 
• 498-07-7 levoglucosan 
• 23643-29-0 1,6-anhydro-4-O-(4-toluenesulfonyl)-β-D-glucopyranose 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 29332-85-2 1,6-anhydro-2,4-dideoxy-2,4-difluoro-β-D-glucopyranoside 

Relevant academic research and scientific papers

Exploring the Chemistry of Non-sticky Sugars: Synthesis of Polyfluorinated Carbohydrate Analogues of d-Allopyranose

There is a growing interest in the preparation of polyfluorinated carbohydrates. A limited number of fluorohexopyranosides have been used in biological investigations because of the synthetic challenge they present. Hence, we report the synthesis of fluor

A short synthesis of 4-deoxy-4-fluoroglucosaminides: Methylumbelliferyl N-acetyl-4-deoxy-4-fluoro-β-D-glucosaminide

A convenient method of synthesis of 1,6-anhydro-4-deoxy-2-O-tosyl-4-fluoro- β-D-glucopyranose by fusion of 1,6;3,4-dianhydro-2-O-tosyl-β-D- galactopyranose with 2,4,6-trimethylpyridinium fluoride was found. By a successive action of ammonia, methyl trifluoroacetate, and acetic anhydride, the resulting compound was transformed into 1,6-anhydro-3-O-acetyl-2,4-dideoxy-2- trifluoroacetamido-4-fluoro-β-D-glucopyranose, which was converted into 3,6-di-O-acetyl-2,4-dideoxy-2-trifluoroacetamido-4-fluoro-αD- glucopyranosyl fluoride by the reaction with HF/Py. The resulting fluoride was further used as a glycosyl donor in the synthesis of methylumbelliferyl N-acetyl-4-deoxy-4-fluoro-β-D-glucosaminide.