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2,4-Imidazolidinedione, 1-nitroso-3-phenyl-, also known as INP-101, is a chemical compound with potential therapeutic applications. It is characterized by its ability to react with hemoglobin, forming covalent adducts that inhibit the polymerization of sickle hemoglobin. This property makes it a promising candidate for the treatment of sickle cell disease and other hemoglobinopathies. Furthermore, INP-101 has been associated with anti-inflammatory and antioxidant effects, although further research is required to elucidate its full mechanisms of action and therapeutic potential.

33557-83-4

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33557-83-4 Usage

Uses

Used in Pharmaceutical Industry:
2,4-Imidazolidinedione, 1-nitroso-3-phenylis used as a therapeutic agent for the treatment of sickle cell disease and other hemoglobinopathies. It functions by reacting with hemoglobin to form covalent adducts, which prevent the polymerization of sickle hemoglobin and reduce the severity of sickle cell disease symptoms.
Used in Research and Development:
INP-101 is used in research settings to explore its potential anti-inflammatory and antioxidant properties. Further studies are needed to fully understand its mechanisms of action and to assess its potential therapeutic applications in various medical conditions beyond sickle cell disease and hemoglobinopathies.

Check Digit Verification of cas no

The CAS Registry Mumber 33557-83-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,5,5 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 33557-83:
(7*3)+(6*3)+(5*5)+(4*5)+(3*7)+(2*8)+(1*3)=124
124 % 10 = 4
So 33557-83-4 is a valid CAS Registry Number.

33557-83-4Downstream Products

33557-83-4Relevant academic research and scientific papers

SYNTHESIS AND NITROSATION OF 3- AND 3,5-SUBSTITUTED HYDANTOINS

Klimavichyus, K.-A. V.,Lutsenko, V. V.,Paulauskaite, G. V.,Mikul'skis, P. P.,Bal'chitis, G. A.,Ionushauskas, S. L.

, p. 1160 - 1162 (2007/10/02)

The cyclization of N-alkylated(arylated) α-ureidocarboxylic acids gives a series of 3-mono- and 3,5-disubstituted hydantoins, and nitrosation of the latter yields their nitroso derivatives.The rotational isomerism of 3-(α-naphthyl)hydantoins has been stud

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