335599-07-0

Basic information

• Product Name: 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI)
• Synonyms: 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI);Ethyl 3-oxa-bicyclo[3.1.0]hexane-6-carboxylate
• CAS NO: 335599-07-0
• Molecular Formula: C8H12O3
• Molecular Weight: 156.18
• Product Categories: CARBOXYLICESTER
• Mol File: 335599-07-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI)(335599-07-0)
• EPA Substance Registry System: 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI)(335599-07-0)

Safety Data

• Hazardous Substances Data: 335599-07-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI) is utilized as a key intermediate in organic synthesis for its ability to participate in various chemical reactions. Its unique ring structure allows it to be a valuable component in the creation of complex organic molecules, contributing to the development of new chemical entities.
Used in Pharmaceutical Applications:
In the pharmaceutical industry, 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI) is employed as a precursor in the production of pharmaceutical drugs. Its potential medicinal properties make it a candidate for further research and development, potentially leading to the discovery of new therapeutic agents.
Used in Chemical Reactions:
3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,ethylester(9CI) is used as a reactant in a variety of chemical reactions due to its reactivity and the stability of its bicyclic structure. This allows for the formation of new compounds with potential applications in different fields, including materials science and specialty chemicals.

Upstream product

• 1708-29-8 2,5-dihydrofuran 
• 623-73-4 diazoacetic acid ethyl ester 
• 5417-32-3 1,3-dioxa-5-cycloheptene 

Downstream Products

• 693248-53-2 3-Oxabicyclo<3.1.0>hexan-exo-6-carbonsaeure 
• 1398833-81-2 (3-oxa-bicyclo[3.1.0]hexan-6-yl)methanol 

Relevant articles and documents

ALKYNYL QUINAZOLINE COMPOUNDS

The present disclosure relates to compounds of Formula (I'): and pharmaceutically acceptable salts and stereoisomers thereof. The present disclosure also relates to methods of preparation these compounds, compositions comprising these compounds, and methods of using them in the prevention or treatment of abnormal cell growth in mammals, especially humans.

TGF-betaR1 inhibitor and application thereof

The invention belongs to the field of medical chemistry, and particularly relates to a compound serving as a TGF-betaR1 inhibitor and application of the compound. Specifically, the invention providesa compound shown as a formula I or an isomer, a pharmaceutically acceptable salt, a solvate, a crystal or a prodrug thereof, a preparation method of the compounds, a pharmaceutical composition containing the compounds and application of the compounds or the composition to treatment and/or prevention of TGF-betaR1 related diseases, such as cancers, tissue hyperplasia diseases, fibrosis and inflammatory diseases. The compound provided by the invention shows significant inhibitory activity on TGF-betaR1 kinase, and is very expected to become a therapeutic agent for TGF-betaR1 related diseases.

Bcl-2 INHIBITORS

Disclosed herein is a compound of Formula (I) for inhibiting Bcl-2 and treating disease associated with undesirable bcl-2 activity (Bcl-2 related diseases), a method of using the compounds disclosed herein for treating dysregulated apoptotic diseases including cancers and treating autoimmune disease, and a pharmaceutical composition comprising the same.

Heterocylic antiviral compounds

This invention relates to piperidine derivatives of formula I wherein R1, R2, R3 and R4 are as defined herein useful in the treatment of a variety of disorders, including those in which the modulation of CCR5 re

Substituted acrylamido-penicillanic acid derivatives

Compounds of formula (I) and their derivatives: wherein X is hydrogen or a group NHR1, wherein R1 is hydrogen or an amino protecting group, and R is an optionally substituted spiro, fused or bridged bicyclic group optionally containing one or more heteroatoms selected from oxygen, nitrogen and sulphur, are new and useful in the treatment of bacterial infections in humans and animals.

(5RS,7RS)-7-Methoxy-1,3-dioxacyclooct-5(E)-ene. Synthesis of a Stable Bishetero-trans-cyclooctene, a New Heterocyclic System

Deamination of N-(3,5-dioxabicyclooct-exo-8-yl)-N-nitrosourea (12) with sodium hydrogencarbonate in methanol produced the bicyclic ether 13 and the title compound 14.The latter is quickly isomerized to the cis olefine 15 by a trace of iodine at 30 deg C and gives the cycloadduct 16 with 2,3-dimethyl-1,3-butadiene at 60 deg C. 14 and 15 are the first examples of 1,3-dioxocine derivatives.