335646-02-1

Basic information

• Product Name: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[(2S)-2-(hydroxydiphenylmethyl)-1-pyrrolidinyl]-
• CAS NO: 335646-02-1
• Molecular Formula: C23H23NO4
• Molecular Weight: 377.44
• Mol File: 335646-02-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[(2S)-2-(hydroxydiphenylmethyl)-1-pyrrolidinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[(2S)-2-(hydroxydiphenylmethyl)-1-pyrrolidinyl]-(335646-02-1)
• EPA Substance Registry System: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[(2S)-2-(hydroxydiphenylmethyl)-1-pyrrolidinyl]-(335646-02-1)

Safety Data

• Hazardous Substances Data: 335646-02-1(Hazardous Substances Data)

Upstream product

• 22348-32-9 (S)-diphenylprolinol 
• 5231-87-8 3,4-diethoxy-3-cyclobuten-1,2-dione 

Downstream Products

• 1350968-71-6 C₆₉H₆₉N₇O₉ 
• 1350968-69-2 C₇₂H₆₆N₆O₉ 
• 1350968-70-5 C₇₅H₇₂N₆O₉ 
• 335646-04-3 3-mercapto-4-[(2'S)-2'-(diphenylhydroxymethyl)pyrrolidino]-3-cyclobutene-1,2-dione 

Relevant articles and documents

Chiral monoaminoalcohols and diaminoalcohols of squaric acid: New catalysts for the asymmetric reduction of ketones by borane

Two series of new chiral ligands, squaric acid aminoalcohols and C2-symmetric squaric acid diaminoalcohols have been synthesized. The chiral oxazaborolidines formed in situ from these ligands have been used in the enantioselective borane reduction of prochiral ketones and diketones to afford alcohol products with up to 99% enantiomeric excesses. The structures of the ligands have an obvious effect on the ee of the resulting alcohols.

Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono-and diketones to nitroalkenes

Novel bifunctional chiral squaramide-amine organocatalysts have been developed by rational combination of pyrrolidine and a cinchona alkaloid. The catalysts promoted the enantioselective Michael addition of both mono-and diketones to a broad range of nitr