335650-15-2

Usage

Class

Pyrrolidinecarboxylic acids

Explanation

1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-4-methoxy-, phenylmethyl ester (2S,4R)belongs to a class of chemical compounds called pyrrolidinecarboxylic acids.

Explanation

The compound has a molecular formula of C15H21NO4, indicating the number of carbon (C), hydrogen (H), nitrogen (N), and oxygen (O) atoms in the molecule.
3. Phenylmethyl ester

Explanation

The compound is a phenylmethyl ester, which means it has a phenyl group (a ring structure with a methyl side chain) attached to the carboxyl group of the pyrrolidinecarboxylic acid.

Explanation

The (2S,4R)designation indicates the specific spatial arrangement of atoms in the molecule, which can significantly affect its biological activity.
5. Biological and medicinal properties

Explanation

1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-4-methoxy-, phenylmethyl ester (2S,4R)is known for its potential biological and medicinal properties, making it a subject of interest in pharmaceutical and research applications.
6. Drug development and medicinal chemistry

Explanation

Ongoing research is being conducted on 1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-4-methoxy-, phenylmethyl ester, (2S,4R)- to explore its potential uses in drug development and medicinal chemistry, due to its unique structure and properties.

Stereochemistry

(2S,4R)-

Upstream product

• 96522-37-1 (2S,4R)-1-[(benzyloxy)carbonyl]-4-methoxy-2-pyrrolidinecarboxylic acid 
• 96522-36-0 (2S,4R)-4-methoxypyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 

Downstream Products

• 1372810-16-6 (2S,4R)-N-(benzyloxycarbonyl)-2-(tert-butoxymethyl)-4-methoxypyrrolidine 

Relevant academic research and scientific papers

ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

The present invention is for the anti-inflammatory compounds that have an inhibitory activity against protein tyrosine kinases and their pharmaceutical composition(s) containing the compound as the active ingredient. Since the compounds of the present invention can inhibit multiple protein kinases associated with inflammatory diseases and immune disorders, they are useful for their prevention or treatment.

New optically active 4-alkoxyprolinol ethers derived from trans-4-Hydroxy-L-proline

(2S,4R)-trans-4-Hydroxy-L-proline has been used as thechiral-pool source in the efficient syntheses of optically active protected 4-hydroxyprolinols. After N-acyl protection andester formation, the first ether moiety was introduced maintaining the chiral

BICYCLIC UNSATURATED TERTIARY AMINE COMPOUND

The present invention provides a bicyclic unsaturated tertiary amine compound capable of inhibiting the production of inflammatory cytokines.A compound of the following formula (1): (wherein, A represents pyrrole or pyrazole, R1 represents an aryl group or a heteroaryl group which may be substituted, R2 represents a heteroaryl group which may be substituted, and R3 represents an indolizine group), or a pharmacologically acceptable salt thereof, a pharmacologically acceptable ester thereof or other pharmacologically acceptable derivative thereof.

Indolyl-urea derivatives of thienopyridines useful as antiangiogenic agents, and methods for their use

The invention relates to compounds represented by the formula I and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R1 and R11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.

Tyrosine kinase inhibitors

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.