33593-20-3Relevant academic research and scientific papers
A multicomponent two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-: C] pyridin-4-ones using a solid acid as a recyclable catalyst
Li, Chunmei,Zhang, Furen,Qi, Chenze
supporting information, p. 3109 - 3115 (2019/06/18)
A multicomponent two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-c]pyridin-4-one derivatives has been described. The reactions can be readily performed by mixing inexpensive starting materials using two-step methods under mild condition
Bio-based triacetic acid lactone in the synthesis of azaheterocycles via a ring-opening transformation
Obydennov, Dmitrii L.,El-Tantawy, Asmaa I.,Sosnovskikh, Vyacheslav Ya.
, p. 8943 - 8952 (2018/06/08)
In the present article a new way of converting bio-based triacetic acid lactone (TAL) into azaheterocyclic compounds, such as 4-pyridones, pyrazoles, isoxazolines and isoxazoles, has been found. The main strategy involves the transformation of TAL into re
A Novel One-Pot, Two-Step Reaction for the Synthesis of Indenopyrrolo[3,2- c ]pyridinone Derivatives with a Recyclable Catalyst
Li, Chunmei,Zhang, Furen,Qi, Chenze
supporting information, p. 2707 - 2711 (2018/12/13)
An efficient strategy was developed for the synthesis of indenopyrrolopyridinone derivatives from 4-hydroxy-6-methyl-2 H -pyran-2-one, an amine, and 2,2-dihydroxy-1 H -indene-1,3(2 H)-dione by a one-pot, two-step, four-component process. The one-pot react
Reactivite de la methyl-6 hydroxy-4 pyrone-2 vis-a-vis des amines primaires : synthese de pyridones-2 N-substituees et d'hexanamides intermediaires
Castillo, Simone,Ouadahi, Hamid,Herault, Valentin
, p. 257 - 261 (2007/10/02)
In the well-documented (1-7) reaction of ammonia or primary amines with 2-pyrones leading to pyridones, the aliphatic intermediates have never been isolated, except for the reaction of 1 with aniline (8).In this work, the reaction of 4-hydroxy-6-methyl-2-pyrone 1 with various primary amines is studied.Three 5-amino-3-oxo-4-hexaneamides 3 are isolated for the first time and characterized by NMR, IR and mass spectra.The corresponding 4-hydroxy-6-methyl-2-pyridones 4 are obtained by heating intermediates 3.Direct attack of 1 by primary amines yields the same compounds 4 and finally leads to 4-alkyl (or phenyl) amino-6-methyl-2-pyridones 5.Thus, compounds of the type 5 are obtained from 4-hydroxy-6-methyl-2-pyrone 1 in for steps including three successive nucleophilic sustitutions by primary amines.
