33598-21-9

Upstream product

• 6261-22-9 pent-2-yn-1-ol 
• 71-43-2 benzene 
• 10574-76-2 pent-2-ynyl acetate 
• 16635-23-7 phenyltriisopropoxytitanium(IV) 
• 79965-57-4 C₂₅H₂₂ 
• 79965-50-7 C₂₃H₁₈O 
• 79965-61-0 C₃₈H₄₂N₂O₂S 
• 16400-32-1 1-bromo-pent-2-yne 
• 100-58-3 phenylmagnesium bromide 

Relevant academic research and scientific papers

Synthesis of allenes via Nickel-catalyzed cross-coupling reaction of propargylic bromides with grignard reagents

We describe a convenient method for the synthesis of terminal allenes from cross-coupling of propargylic bromide with Grignard reagent. The reaction of propargylic bromide with 1.2 equivalents of Grignard reagent mediated by Ni(acac)2 (2 mol%) and Ph3P (4 mol%) in THF may produce terminal allenes in good yields and high regioselectivities at room temperature. Georg Thieme Verlag Stuttgart · New York.

KETENE-ANTHRACENE ADDUCT, A PRECURSOR OF SUBSTITUTED ACETYLENES

The ketene-anhracene adduct 1 serves as a good precursor in the synthesis of substituted acetylenes, in wich the key step is the retro Diels-Alder reaction.