33599-46-1

Basic information

• Product Name: α-L-gulopyranuronic acid
• Synonyms: α-L-gulopyranuronic acid
• CAS NO: 33599-46-1
• Molecular Weight: 194.141
• Mol File: 33599-46-1.mol
• Article Data: 147

Chemical Properties

• CAS DataBase Reference: α-L-gulopyranuronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: α-L-gulopyranuronic acid(33599-46-1)
• EPA Substance Registry System: α-L-gulopyranuronic acid(33599-46-1)

Safety Data

• Hazardous Substances Data: 33599-46-1(Hazardous Substances Data)

Upstream product

• 40386-94-5 α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-D-GalpA 
• 40386-95-6 α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-D-GalpA 
• 40307-14-0 α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-α-D-GalpA-(1->4)-D-GalpA 
• 40307-13-9 tri-galacturonic acid 
• 73977-52-3 2,4-di-O-acetyl-β-methyl-D-galactopyranosideuronic acid γ-lactone 
• 6294-16-2 D-galacturonic acid 
• 902141-54-2 di(D-galactosiduronic) acid 
• 18486-47-0 methyl D-galactopyranuronate 
• 56317-11-4 apigenin 7-O-β-D-galacturonopyranoside 
• 56324-53-9 luteolin-7-O-β-D-galacturonide 
• 488148-26-1 chrysin-7-O-β-D-galacturonide 
• 186581-53-3 diazomethane 
• 107091-09-8 3-O-β-D-galactopyranosyl-(1->2)-<β-D-xylopyranosyl-(1->3)>-β-D-glucuronopyranosyl quillaic acid 28-O-β-D-apiofuranosyl-(1->3)-β-D-xylopyranosyl-(1->4)-<β-D-glucopyranosyl-(1->3)>-α-L-rhamnopyranosyl-(1->2)-β-D-fucopyranoside. 
• 17685-07-3 O¹-Propyl-β-D-glucopyranuronsaeure 

Downstream Products

• 5155-54-4 methyl (methyl α-D-galacturonopyranoside)uronate 
• 18486-38-9 methyl β-D-glucuronopyranoside methyl ester 
• 133640-39-8 methyl α,β-D-glucopyranosidurono-6,3-lactone 
• 17681-01-5 methyl β-D-glucofuranosidurono-6,3-lactone 
• 17681-01-5 methyl α-D-glucofuranosidurono-6,3-lactone 
• 18486-51-6 1-O-methyl-α-D-glucopyranuronic acid methyl ester 
• 499-05-8 comanic acid 
• 95722-14-8 1,2,3-tri-O-acetyl-4-deoxy-β-L-threo-4-hexenopyranuronic acid 
• 62133-77-1 1,2,3,4-tetra-O-acetyl-β-D-glucopyranuronic acid 
• 83023-73-8 (2S,3S,4S,5R,6R)-3,4,5,6-tetraacetoxytetrahydro-2H-pyran-2-carboxylic acid 
• 18486-47-0 methyl D-galactopyranuronate 
• 153321-67-6 Retinoic Acid glucuronide 
• 239083-75-1 D-galacturonic acid (E)-2-nitrophenylhydrazone 
• 147-73-9 meso-tartaric acid 

Relevant articles and documents

Structure-activity studies of glucose transfer: Determination of the spontaneous rates of hydrolysis of uridine 5′-diphospho-α-D-glucose (UDPG) and uridine 5′-diphospho-α-D-glucuronic acid (UDPGA)

The pH-rate profiles for the hydrolysis of uridine 5′-diphospho-α-D-glucose (UDPG) and uridine 5′-diphospho-α-D-glucuronic acid (UDPGA) in aqueous solution have been measured. The results obtained and a comparison with other data suggests that the mechanism of hydrolysis of each activated glycosyl-donor at pH 1-4 probably involves the slow ionisation, via an SN1 process, of the neutral molecule to a glycosyl ion and UDP. From these data, the catalytic power (kcat/kuncat) of the glycosyltransferases has been estimated for the first time to be in the order of 1011-13.

A Reusable Column Method Using Glycopolymer-Functionalized Resins for Capture–Detection of Proteins and Escherichia coli

The use of glycopolymer-functionalized resins (Resin–Glc), as a solid support, in?column mode for bacterial/protein capture and quantification is explored. The Resin–Glc is synthesized?from commercially available chloromethylated polystyrene?resin and glycopolymer, and is characterized by fourier transform infrared spectroscopy, thermogravimetry, and elemental analysis. The percentage of glycopolymer functionalized on Resin–Glc is accounted to be 5 wt%. The ability of Resin–Glc to selectively capture lectin, Concanavalin A, over Peanut Agglutinin, reversibly, is demonstrated for six cycles of experiments. The bacterial sequestration study using SYBR (Synergy Brands, Inc.) Green I tagged?Escherichia coli/Staphylococcus aureus?reveals the ability of Resin–Glc to selectively capture?E. coli?over?S. aureus. The quantification of captured cells in the column is carried out by enzymatic colorimetric assay using methylumbelliferyl glucuronide?as the substrate. The?E. coli?capture studies reveal a consistent capture efficiency of 105?CFU (Colony Forming Units) g?1 over six cycles. Studies with spiked tap water samples show satisfactory results for?E. coli?cell densities ranging from 102 to 107?CFU mL?1. The method portrayed can serve as a basis for the development of a reusable solid support in capture and detection of proteins and bacteria.

Isolation and identification of two new sargentodoxosides from Sargentodoxa cuneata and their agonistic effects against FXR

Sargentodoxa cuneata (Oliv.) Rehd. et Wils is a traditional Chinese medicine to treat acute appendicitis, rheumarthritis, abdominal pain, and painful menstruation for a long history. The investigation of S. cuneata led to the isolation and identification of twenty-three secondary metabolites, including two new compounds, sargentodoxosides A (1) and B (2), and twenty-one known ones (3-23). Their structural characterization was conducted by HRESIMS, 1 D and 2 D NMR spectra. All the isolated compounds were assayed for their agonistic activities against the farnesoid X receptor (FXR). Nine of the isolated compounds displayed significant agonistic effects against FXR at 0.1 μM, suggesting that they could be served as potential agents for the development of FXR agonists.