33656-63-2Relevant academic research and scientific papers
Synthesis of Fused Imidazole-Containing Ring Systems via Dual Oxidative Amination of C(sp3)-H Bonds
Castanedo, Georgette,Liu, Yanzhou,Crawford, James J.,Braun, Marie-Gabrielle
, p. 8617 - 8624 (2016)
A general and efficient method for a metal-free one-pot synthesis of highly substituted fused imidazole-containing 5,5- and 5,6-fused bicyclic heterocycles is described. Starting from commercially available substrates and reagents, the reaction proceeds through two C-N bond formations and an oxidative dehydrogenation to form highly substituted products in good to excellent yield.
AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES
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Page/Page column 29-30, (2010/04/03)
Aminopyridopyrazinone derivatives useful in treating disorders that are mediated by adenosine receptor function, including neurodegenerative diseases and inflammation, are disclosed. Pharmaceutical compositions, methods of treatment and use, involving the disclosed compounds, are also disclosed.
