336628-49-0

Basic information

• Product Name: 1,3-dichloro-2-propyl (S)-N-(1-phenylethyl)carbamate
• Synonyms: 1,3-dichloro-2-propyl (S)-N-(1-phenylethyl)carbamate
• CAS NO: 336628-49-0
• Molecular Weight: 276.163
• Mol File: 336628-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-dichloro-2-propyl (S)-N-(1-phenylethyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dichloro-2-propyl (S)-N-(1-phenylethyl)carbamate(336628-49-0)
• EPA Substance Registry System: 1,3-dichloro-2-propyl (S)-N-(1-phenylethyl)carbamate(336628-49-0)

Safety Data

• Hazardous Substances Data: 336628-49-0(Hazardous Substances Data)

Upstream product

• 55183-48-7 chlorocarbonic acid-(β,β'-dichloro-isopropyl ester) 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 96-23-1 1,3-Dichloro-2-propanol 
• 14649-03-7 (S)-phenylethyl isocyanate 

Downstream Products

• 115914-08-4 (S)-N-(1-phenylethyl)prop-2-en-1-amine 
• 336628-52-5 (5R,1'S)-5-chloromethyl-3-(1'-phenylethyl)-2-oxazolidinone 
• 336628-55-8 (5S,1'S)-5-chloromethyl-3-(1'-phenylethyl)-2-oxazolidinone 

Relevant articles and documents

A three-step synthesis of optically active 5-halomethyl-2-oxazolidinones; asymmetric desymmetrization of prochiral 1,3-dihalo-2-propyl carbamates

Optically active 5-bromomethyl-2-oxazolidinones (2a and 3a) and 5-chloromethyl-2-oxazolidinones (2b and 3b) were readily prepared from prochiral 1,3-dibromo-2-propanol (7a) and 1,3-dichloro-2-propanol (7b) by a three-step sequence involving formation of carbamates (6a-c) followed by asymmetric desymmetrization (up to 50% de) and debenzylation by anisole-methanesulfonic acid system.