3367-89-3Relevant academic research and scientific papers
Indolinone derivatives and their use in treating disease-states such as cancer
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Page/Page column 43, (2010/02/11)
Indolinone derivatives, such as compounds of the formula (I): wherein A, m, n, R1, R2, R3, R5 and R6 are described herein, are disclosed herein as being useful in treating mammal having disease-states alleviated by the inhibition of PDK-1 activity.
Influence of the terminal amide fragment geometry in some 3-arylideneindolin-2(1H)-ones on their 5-HT1A/5-HT2A receptor activity1
Mokrosz, Maria J.,Charakchieva-Minol, Sijka,Koziol, Aneta,Klodzinska, Aleksandra,Chojnacka-Wojcik, Ewa
, p. 1229 - 1231 (2007/10/03)
Several 1,4-disubstituted arylpiperazine derivatives of 3-arylideneindolin-2(1H)-one (Z and E isomers) were tested for their 5-HT1A and 5-HT2A receptor activity in vitro and in vivo. It was shown that introduction of 3-arylidene subs
