33673-73-3Relevant academic research and scientific papers
Synthesis of 3-functionalized 3-methylazetidines
Stankovi?, Sonja,D'Hooghe, Matthias,Abbaspour Tehrani, Kourosch,De Kimpe, Norbert
scheme or table, p. 107 - 110 (2012/01/17)
1-t-Butyl- and 1-(4-methylbenzyl)-3-bromo-3-methylazetidines were prepared from the corresponding N-(2,3-dibromo-2-methylpropylidene)alkylamines and their propensity to undergo nucleophilic substitution at the 3-position by different nucleophiles was asse
Baker's yeast mediated biohydrogenation of sulphur-functionalised methacrolein derivatives. Stereochemical aspects of the reaction and preparation of the two enantiomers of useful C4 bifunctional chiral synthons
Serra, Stefano,Fuganti, Claudio
, p. 2191 - 2196 (2007/10/03)
The baker's yeast mediated reduction of sulphur-functionalised methacroleins 11, 15 and 18 leads to the preparation of the bifunctional methyl branched C4 chiral synthons 6 and 7. The stereochemical aspects of the biohydrogenation have been investigated. Both the oxidation state of sulphur and the isomeric position of the double bond affected the enantioselectivity of the reduction strongly, thus, offering access to the two enantiomeric forms of 6 and 7.
SYNTHESIS AND REACTIONS OF SUBSTITUTED ACROLEINS.
Saprygina,Zlot-skii,Rakhmankulov
, p. 862 - 866 (2007/10/02)
In this work we examined methods for obtaining 2-alkylacroleins and their derivatives that would render these compounds as cheap and readily available products of organic synthesis. Using aldehydes we show that ethylene glycol, glycerin, and pentaerythritol in the presence of acid catalysts react primarily at the carbonyl group. Maximal yields (50-80%) were obtained when using the cation exchanger KU-2 as the acid catalyst, which also simplified the isolation of the desired products. The 2-alkyl-1,3-dioxacyclanes obtained are of particular interest as monomers, comonomers, and intermediate products of organic synthesis.
Monoozonolyses of Acyclic Conjugated Dienes
Griesbaum, Karl,Zwick, Gerhard
, p. 3041 - 3057 (2007/10/02)
Monoozonolyses of isoprene (1a), 2-methyl-3-phenyl-1,3-butadiene (1b), 2,3-diphenyl-1,3-butadiene (25), and 2,3,4,5-tetramethyl-2,4-hexadiene (34) have been examined in pentane and in methanol.The dienes 1a, b and 25 afforded all possible α,β-unsaturated monoozonides and α,β-unsaturated methoxy hydroperoxides, respectively, whereas diene 34 gave no ozonide and no α,β-unsaturated methoxy hydroperoxide.From the dienens 25 and 34, the corresponding monoepoxides have been formed additionally.The results allow some conclusions concerning the regioselectivity of ozone attack at the unsymmetrically substituted dienes 1a, b as well as concerning the cleavage directions of primary ozonides.
