33682-87-0

Usage

Physical State

Pale yellow to brownish yellow liquid

Odor

Strong odor

Primary Uses

Production of pharmaceuticals
Production of pesticides
Production of dyes

Other Uses

Intermediate in organic synthesis
Manufacturing of fragrances
Manufacturing of flavorings

Hazard Classification

Classified as a hazardous chemical

Hazards

Can cause irritation to the eyes
Can cause irritation to the skin
Can cause irritation to the respiratory tract

Safety Measures

Handle with caution
Use appropriate safety measures when working with it

Upstream product

• 79-46-9 2-nitropropane 
• 2680-03-7 N,N-Dimethylacrylamide 
• 104-88-1 4-chlorobenzaldehyde 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 49581-85-3 α-(1-amino-1-methylethyl)-4-chlorobenzenemethanol 
• 79-46-9 2-nitropropane 
• 104-88-1 4-chlorobenzaldehyde 
• 74261-44-2 α-nitro-p-chloroisobutyrophenone 
• 343228-89-7 1-(4-Chloro-phenyl)-2-methyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-propan-1-ol 
• 49581-84-2 2-Methyl-1-p-chlorphenyl-2-benzylamino-1-propanol 
• 18713-58-1 1-(4-chlorophenyl)-2-methylpropan-1-one 

Relevant academic research and scientific papers

Catalytic intermolecular aldol reactions of transient amide enolates in domino Michael/aldol reactions of nitroalkanes, acrylamides, and aldehydes

Three-component reactions of nitroalkanes, acrylamides, and aldehydes by using a catalytic amount of KOH in DMSO gave β′-hydroxy-γ-nitro amides. Mechanistic studies suggested that the reactions proceeded by domino Michael/aldol reactions. The highly nucle

Tandem Hass-Bender/Henry reaction for the synthesis of dimethylnitro alcohols from benzylic halides

Dimethylnitro alcohols are constructed in a one-pot process from benzylic halides and 2-nitropropane. The use of tetrabutylammonium fluoride (TBAF) as the promoter is essential for this tandem Hass-Bender/Henry reaction to proceed.