33694-64-3Relevant academic research and scientific papers
Cu-Promoted [2 + 2] cycloaddition of 1,4-bisallenes
Kitagaki, Shinji,Kajita, Mikihito,Narita, Syu,Mukai, Chisato
supporting information; experimental part, p. 1366 - 1369 (2012/05/20)
The thermal reaction of 1,4-bisallenes with the aid of Cu salt/amine significantly suppressed the formal [3,3] sigmatropic rearrangement resulting in the highly selective formation of the bicyclo[4.2.0]octadiene framework. This reaction could be applied to the one-pot synthesis of bicyclo[4.2.0]octadienes from 1,5-hexadiynes via the Crabbe homologation.
