33723-35-2

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 3179-10-0 1-methoxy-4-(2-nitro-vinyl)-benzene 

Relevant academic research and scientific papers

An efficient class of bis-NHC salts: Applications in Pd-catalyzed reactions under mild reaction conditions

This study describes an efficient class of bis-N-heterocyclic carbene (bis-NHC) salts that can be easily made from commercially available and inexpensive starting materials. The application of these salts to Pd-catalyzed reactions is described. The palladium (Pd) catalyst generated in situ was highly effective under mild reaction conditions.

Rose bengal as photocatalyst: Visible light-mediated Friedel-Crafts alkylation of indoles with nitroalkenes in water

A novel and facile visible-light-mediated alkylation of indoles and nitroalkenes has been developed. In this protocol, rose bengal acts as a photosensitizer, and environmentally benign water was used as the green and efficient reaction medium. Indoles rea

D-camphor-10-sulfonic acid: A water compatible organocatalyst for Friedel-Crafts reaction of indoles with electron deficient olefins

A recyclable natural product derived Bronsted acid (D-CSA) catalyzes the Friedel-Crafts addition of indole derivatives to nitroalkenes and enones in water at room temperature in good to excellent yields (71-98%).

An efficient and clean Michael addition of indoles to electron-deficient olefins under solvent- and catalyst-free condition

An efficient Michael addition of indoles to electron-deficient olefins under solvent- and catalyst-free condition afforded biologically important 3-substituted indole derivatives in good to excellent yields was reported. The acidic N-H proton of indole pl

Synthesis, structural characterization of benzimidazole-functionalized Ni(II) and Hg(II) N-heterocyclic carbene complexes and their applications as efficient catalysts for Friedel-Crafts alkylations

[Ni(L1)2](PF6)2 (3a, L 1 = 3-(1-ethyl-1H-benzimidazol-2-yl)methyl)-1-((6-methylpyridin-2-yl) methyl)imidazolyl-idene), [Ni(L2)2(CH3CN)] (PF6)2 (3

Montmorillonite K10-catalyzed michael addition of indoles to nitroolefins under solvent-free conditions

Montmorillonite K10 is a very inexpensive and readily available reagent and efficiently catalyzes the Michael addition of indoles to nitroolefins under solvent-free conditions. Reasonable to excellent yields of the desired products were obtained in most c

Simple and efficient Friedel-Crafts alkylation of 1H-indole with electron-deficient alkenes promoted by zinc acetate

An efficient method for the Friedel-Crafts alkylation of 1H-indole with nitro alkenes in the presence of zinc acetate is described. The procedure is applicable to a variety of nitro alkenes and substituted indoles, and the yields are very high.

Silica sulfuric acid-catalyzed Friedel-Crafts alkylation of indoles with nitro olefins

The 1,4-conjugate addition of indoles to nitro olefins was efficiently carried out using an environmentally benign catalyst, silica sulfuric acid, at ambient temperature. Copyright Taylor & Francis Group, LLC.

Sulfamic acid-catalyzed Michael addition of indoles and pyrrole to electron-deficient nitroolefins under solvent-free condition

Sulfamic acid (SA) effectively catalyze the Michael addition of indoles and pyrrole to nitroolefins under solvent-free condition to afford the corresponding Michael adducts in good to excellent yields.