337358-76-6

Upstream product

• 1360114-12-0 (3-chloro-phenyl)-(2,6-dichloro-pyridin-3-yl)-methanol 
• 587-04-2 m-Chlorobenzaldehyde 
• 2402-78-0 2,6-dichloropyridine 

Downstream Products

• 1360113-81-0 2-(N-benzyl-N-(tert-butyloxycarbonyl)amino)-N-(6-chloro-3-(3-chlorobenzoyl)pyridin-2-yl)acetamide 
• 1360113-85-4 2-(bis(4-methoxybenzyl)amino)-N-(6-chloro-3-(3-chlorobenzoyl)pyridin-2-yl)acetamide 
• 1360113-98-9 2-[9H-fluoren-9-ylmethoxycarbonyl]amino-N-(6-chloro-3-(3-chlorobenzoyl)pyridin-2-yl)-N-methyl-acetamide 
• 1360113-71-8 2-((benzyloxycarbonyl)amino)-N-(6-chloro-3-(3-chlorobenzoyl)pyridin-2-yl)acetamide 
• 1360114-04-0 2-(benzyloxycarbamoyl)-N-(6-chloro-3-(3-chlorobenzoyl)pyridin-2-yl)-N-methylacetamide 
• 337358-77-7 6-chloro-3-(3-chlorobenzoyl)-2-ethylaminopyridine 

Relevant academic research and scientific papers

Novel access to 1,4-benzodiazepin-2-ones via the Buchwald reaction and application to the synthesis of novel heterocyclics

A new two step strategy for the preparation of 1,4-benzodiazepin-2-ones has been developed starting from the 2-halogenobenzophenone under Buchwald conditions (Pd(OAc)2, XantPhos, Cs2CO3, dioxane 100 °C). This strategy has

NAPHTHYRIDINE DERIVATIVES

2-Oxo-1,2-dihydro-1,8-naphthyridine derivatives characterized by bearing a specific substituent, -X-R6, at the 3-position and a cyclic substituent, R5, at the 4-position; or salts thereof. The derivatives and the salts are useful as drugs, particularly preventive or therapeutic agents for respiratory diseases related to PDE IV.