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8-Nitro-D-guanosine is a highly reactive redox-active nucleic acid derivative that is formed in cellular RNA as a biomarker of exposure to reactive nitrogen species. It is characterized by its orange solid appearance and is defined as guanosine substituted at the purine 8-position by a nitro group (ChEBI).

337536-53-5

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337536-53-5 Usage

Uses

Used in Research and Diagnostics:
8-Nitro-D-guanosine is used as a biomarker for research and diagnostics, specifically in the detection of exposure to reactive nitrogen species. Its presence in cellular RNA indicates potential involvement in various biological processes and conditions.
Used in Anticancer Applications:
8-Nitro-D-guanosine is used as a potential therapeutic agent in the field of oncology. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis, making it a subject of interest for further research and development in cancer treatment.
Used in Pharmaceutical Industry:
8-Nitro-D-guanosine is used as a chemical intermediate in the pharmaceutical industry for the synthesis of various drugs and drug candidates. Its unique chemical properties and reactivity make it a valuable compound for the development of novel therapeutics.
Used in Environmental Monitoring:
8-Nitro-D-guanosine can be used as an environmental monitoring tool to assess the level of exposure to reactive nitrogen species in various ecosystems. This information can be crucial for understanding the impact of pollution and other environmental factors on public health and ecosystem health.

Check Digit Verification of cas no

The CAS Registry Mumber 337536-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,7,5,3 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 337536-53:
(8*3)+(7*3)+(6*7)+(5*5)+(4*3)+(3*6)+(2*5)+(1*3)=155
155 % 10 = 5
So 337536-53-5 is a valid CAS Registry Number.

337536-53-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-Nitroguanosine

1.2 Other means of identification

Product number -
Other names 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-nitro-3H-purin-6-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:337536-53-5 SDS

337536-53-5Upstream product

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