33758-19-9Relevant academic research and scientific papers
An improved procedure for the synthesis of N-bromoacetyl-β- glycopyranosylamines, derivatives of mono- and disaccharides
Likhosherstov,Novikova,Zheltova,Shibaev
, p. 709 - 713 (2007/10/03)
An improved procedure for the synthesis of N-bromoacetyl-β- glycopyranosylamines from the corresponding β-glycosylamines was developed. The procedure is applicable to a wide range of derivatives of monosaccharides (hexoses, 2-acetamido-2-deoxyhexoses, hexuronamides, and 6-deoxyhexoses) and some disaccharides. For the derivatives of pentoses and 2-deoxyhexoses, the use of the corresponding β-glycosylammonium carbamates was found to be more convenient. N-Bromoacetyl-β-glycopyranosylamines derived from D-mannose, L-rhamnose, D-glucuronamide, 2-deoxy-D-arabino-hexose, 2-deoxy-D-lyxo-hexose, and melibiose were obtained for the first time.
Chemoselective elaboration of O-linked glycopeptide mimetics by alkylation of 3-thioGalNAc
Marcaurelle,Bertozzi
, p. 1587 - 1595 (2007/10/03)
A critical branch point in mucin-type oligosaccharides is the β1 → 3 glycosidic linkage to the core α-N-acetylgalactosamine (GalNAc) residue. We report here a strategy for the synthesis of O-linked glycopeptide analogues that replaces this linkage with a
