33761-27-2

Basic information

• Product Name: Oxazolo[5,4-b]pyridine, 2-(4-methylphenyl)-
• CAS NO: 33761-27-2
• Molecular Formula: C13H10N2O
• Molecular Weight: 210.235
• Mol File: 33761-27-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Oxazolo[5,4-b]pyridine, 2-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazolo[5,4-b]pyridine, 2-(4-methylphenyl)-(33761-27-2)
• EPA Substance Registry System: Oxazolo[5,4-b]pyridine, 2-(4-methylphenyl)-(33761-27-2)

Safety Data

• Hazardous Substances Data: 33761-27-2(Hazardous Substances Data)

Upstream product

• 874-60-2 4-methyl-benzoyl chloride 
• 6298-19-7 2-chloro-3-aminopyridine 
• 33761-26-1 3-(p-toluoylamino)-2-chloropyridine 
• 52334-63-1 4-methyl-N-(2-oxo-1,2-dihydro-pyridin-3-yl)-benzamide 

Relevant articles and documents

TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY

There are disclosed compound of Formula (1): A1, A2, A3 and A4 which may be the same or different, represent N or CR1, X is a divalent group selected from O, S(O)n, C=W, NR4, NC(=O)R5 and CR6R7, W is O, S, NR20, Y is N or CR8, one of R4, R5, R6, R8, R9 and NR20 represents - L -R3, in which L is a single bond or a linker group, additionally, R1, R3 - R9, which may be the same or different, independently represent hydrogen or a substituent and R20 represents hydrogen, hydroxyl, alkyl optionally substituted by aryl, alkoxy optionally substituted by aryl, aryl, CN, optionally substituted alkoxy, optionally substituted aryloxy, optionally substitute alkanoyl, optionally substituted aroyl, NO2, NR30R31, in which R30 and R31, which may be the same or different, represent hydrogen, optionally substituted alkyl or optionally substituted aryl; additionally, one of R30 and R31 may represent optionally substituted alkanoyl or optionally substituted aroyl, n represents an integer from 0 to 2, in addition, when an adjacent pair of A1 - A4 each represent CR1, then the adjacent carbon atoms, together with their substituents may form a ring B, when X is CR6R7, R6 and R7, together with the carbon atom to which they are attached may form a ring C, or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the therapeutic and/or prophylactic treatment of Duchenne muscular dystrophy, Becker muscular dystrophy or cachexia.

Anti-inflammatory oxazole[4,5-b]pyridines

The various isomers of oxazolo- and thiazolopyridines having utility as antiinflammatory, antipyretic and analgesic agents are prepared by condensation of an appropriate amino-hydroxypyridine or amino-mercaptopyridine with a carboxylic acid, halide or anhydride.