337968-47-5Relevant articles and documents
Asymmetric syntheses of trisubstituted tetrahydrofuran lignans, sesaminone and 4-epidihydrosesamin
Yoda,Kimura,Takabe
, p. 400 - 402 (2007/10/03)
An efficient and stereodefined process is described for the preparation of 2,3,4-trisubstituted tetrahydrofuran lignans, sesaminone and 4-epidihydrosesamin. The synthetic strategy is based on the similar chemoselective hydrogenation of functionalized lactol derivatives, elaborated through asymmetric condensation of a 4,5-trans-disubstituted lactone.