3380-80-1 Usage
General Description
1-(4-chlorophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline hydrochloride is a chemical compound with potential biological activity. It is a hydrochloride salt form of beta-carboline, which is a naturally occurring alkaloid found in various plants. 1-(4-chlorophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline hydrochloride has been studied for its potential pharmacological effects, including its activity as a central nervous system stimulant and hallucinogenic drug. It has also been investigated for its potential role in the treatment of neurodegenerative diseases and as a potential therapeutic agent for various psychiatric disorders. Additionally, it has been studied for its potential role in cancer therapy due to its ability to induce apoptosis in cancer cells. Overall, 1-(4-chlorophenyl)-2,3,4,9-tetrahydro-1H-beta-carboline hydrochloride is a compound with diverse pharmacological activities and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 3380-80-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,8 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3380-80:
(6*3)+(5*3)+(4*8)+(3*0)+(2*8)+(1*0)=81
81 % 10 = 1
So 3380-80-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H15ClN2.ClH/c18-12-7-5-11(6-8-12)16-17-14(9-10-19-16)13-3-1-2-4-15(13)20-17;/h1-8,16,19-20H,9-10H2;1H
3380-80-1Relevant articles and documents
Asymmetric Biocatalytic Synthesis of 1-Aryltetrahydro-β-carbolines Enabled by “Substrate Walking”
Eger, Elisabeth,Iding, Hans,Kroutil, Wolfgang,Kuhn, Bernd,Schrittwieser, Joerg H.,Wetzl, Dennis
supporting information, p. 16281 - 16285 (2020/11/30)
Stereoselective catalysts for the Pictet–Spengler reaction of tryptamines and aldehydes may allow a simple and fast approach to chiral 1-substituted tetrahydro-β-carbolines. Although biocatalysts have previously been employed for the Pictet–Spengler react
AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER
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Paragraph 00569-00570, (2018/10/25)
The present application discloses a method for identifying an agent for the treatment or prevention of cancer or metastatic cancer comprising the steps of contacting stem cell with a potential agent, and identifying an agent that induces differentiation, or inhibits stem cell pluripotency or growth of the stem cell, wherein such agent is determined to be an anti-cancer agent.
