6α-[(2-Amino-1-oxohexyl)amino]penicillanic acid, also known as 6-aminopenicillanic acid (6-APA), is a key intermediate compound in the synthesis of semi-synthetic penicillins. It is derived from the chemical modification of the penicillin nucleus, which involves the removal of the side chain from the parent penicillin molecule. 6-APA serves as a crucial building block for the development of various semi-synthetic penicillins, such as ampicillin and amoxicillin, which possess broader-spectrum antibiotic activity compared to natural penicillins. The chemical structure of 6-APA consists of a β-lactam ring, a thiazolidine ring, and an amino group attached to the 6α position, which allows for the attachment of different side chains to create new penicillin derivatives with improved properties.
The CAS Registry Mumber 3381-65-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,8 and 1 respectively; the second part has 2 digits, 6 and 5 respectively. Calculate Digit Verification of CAS Registry Number 3381-65: (6*3)+(5*3)+(4*8)+(3*1)+(2*6)+(1*5)=85 85 % 10 = 5 So 3381-65-5 is a valid CAS Registry Number.