33821-94-2 Usage
Chemical Properties
Clear colorless to yellow liquid
Uses
2-(3-Bromopropoxy)tetrahydro-2H-pyran may be used in organic synthesis studies.
General Description
The latent alcohol functionality of this bifunctional building block can be generated using aqueous acid.
Check Digit Verification of cas no
The CAS Registry Mumber 33821-94-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,8,2 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 33821-94:
(7*3)+(6*3)+(5*8)+(4*2)+(3*1)+(2*9)+(1*4)=112
112 % 10 = 2
So 33821-94-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H15BrO2/c9-5-3-7-11-8-4-1-2-6-10-8/h8H,1-7H2
33821-94-2Relevant articles and documents
Functionalized aliphatic P2/P2' analogs of HIV-1 protease inhibitor DMP323
Smallheer, Joanne M.,McHugh, Robert J.,Chang, Chong-Hwan,Kaltenbach III, Robert F.,Worley, Tabitha V.,Klabe, Ronald M.,Bacheler, Lee T.,Rayner, Marlene M.,Erickson-Viitanen, Susan,Seitz, Steven P.
, p. 1365 - 1370 (2007/10/03)
A series of analogs of HIV protease inhibitor DMP323 containing functionalized aliphatic P2/P2' groups was prepared and evaluated for HIV protease inhibition and antiviral activity in a cell-based assay. Asymmetric compounds with a 5-hydroxypentyl substituent at P2 and a benzylic substituent at P2' showed increased potency over the corresponding symmetrically substituted analogs.