338426-44-1

Basic information

• Product Name: 1,3,4-Oxadiazole, 2-(4-ethoxyphenyl)-5-(4-methylphenyl)-
• CAS NO: 338426-44-1
• Molecular Formula: C17H16N2O2
• Molecular Weight: 280.326
• Mol File: 338426-44-1.mol

Chemical Properties

• CAS DataBase Reference: 1,3,4-Oxadiazole, 2-(4-ethoxyphenyl)-5-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Oxadiazole, 2-(4-ethoxyphenyl)-5-(4-methylphenyl)-(338426-44-1)
• EPA Substance Registry System: 1,3,4-Oxadiazole, 2-(4-ethoxyphenyl)-5-(4-methylphenyl)-(338426-44-1)

Safety Data

• Hazardous Substances Data: 338426-44-1(Hazardous Substances Data)

Upstream product

• 58586-81-5 4-ethoxybenzohydrazide 
• 765287-28-3 1-(4-Methylbenzoyl)-2-(4-ethyloxybenzoyl)-hydrazine 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 1416793-43-5 C₄₈H₅₄N₄O₁₂ 
• 873691-38-4 2-[(4-bromomethyl)phenyl]-5-(4-ethoxyphenyl)-1,3,4-oxadiazole 
• 1416793-44-6 C₄₀H₃₈N₄O₁₂ 

Relevant articles and documents

Synthesis of a new ratiometric emission Ca2+ indicator for in vivo bioimaging

A novel fluorescent calcium indicator with a 490/582 nm ratiometric emission has been designed and synthesized. The indicator exhibits a highly selective ratiometric emission response to Ca2+ over other metal cations and a large Stokes shift of 202 nm. Moreover, its practical cell imaging capability for intracellular Ca2+ in the resting- and dynamic-state has been demonstrated in human umbilical vein endothelial cells using a confocal laser scanning microscope.

A novel ratiometric emission probe for Ca2+ in living cells

A ratiometric fluorescent probe for Ca2+ based on 1,3,4-oxadiazole derivative has been designed and developed. The probe exhibits a large Stokes shift of 202 nm and a highly selective ratiometric emission response (490/582 nm) to Ca2+ over other metal cations. Additionally, the probe can readily reveal the changes of intracellular Ca2+ concentration in living human umbilical vein endothelial cells. The Royal Society of Chemistry 2013.