338428-57-2Relevant academic research and scientific papers
Cellulose sulphuric acid as a biodegradable and reusable catalyst for the Knoevenagel condensation
Shelke, Kiran F.,Sapkal, Suryakant B.,Niralwad, Kirti S.,Shingate, Bapurao B.,Shingare, Murlidhar S.
, p. 12 - 18 (2010)
A green, mild and efficient method for Knoevenagel condensation of 3-formylchromone/2-chlroquinoline-3-carbaldehyde with active methylene compounds such as Meldrum's acid/ethyl cyanoacetate using biosupported cellulose sulphuric acid (CSA) in the solid-state by grinding under solvent-free condition has been developed. This method provides several advantages including environmental friendliness, shor t reaction times, high yields and a simple work-up procedure. Moreover, the CSA was successfully reused for four cycles without significant loss of activity. Versita Warsaw and Springer-Verlag Berlin Heidelberg.
