338459-02-2

Basic information

• Product Name: 2-benzyloxymethyl-5-hydroxymethyl-1,4-dioxane
• Synonyms: 2-benzyloxymethyl-5-hydroxymethyl-1,4-dioxane
• CAS NO: 338459-02-2
• Molecular Weight: 238.284
• Mol File: 338459-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyloxymethyl-5-hydroxymethyl-1,4-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxymethyl-5-hydroxymethyl-1,4-dioxane(338459-02-2)
• EPA Substance Registry System: 2-benzyloxymethyl-5-hydroxymethyl-1,4-dioxane(338459-02-2)

Safety Data

• Hazardous Substances Data: 338459-02-2(Hazardous Substances Data)

Upstream product

• 338459-01-1 2-acetoxymethyl-5-benzyloxymethyl-1,4-dioxane 

Downstream Products

• 14236-12-5 2,5-Bis(hydroxymethyl)-1,4-dioxane 

Relevant articles and documents

Original synthesis of linear, branched and cyclic oligoglycerol standards

A variety of authentic standards of linear, branched and cyclic oligomers of glycerol, with well-defined structures and degrees of polymerisation from 2 to 5, have been efficiently synthesised. Linear oligomers were obtained by means of a convergent approach based on regioselective opening of bis(epoxides) with solketal; branched compounds were synthesised using oxidative cleavage of the corresponding anhydrohexitols as the key step. A 6-exo-trig halocyclisation reaction involving heteroatom-tethered unsaturated alcohols permitted an efficient synthesis of the precursors of selected cyclic dimers; larger cyclic oligomers were prepared by two one-pot Williamson reactions using a ditriflate derived from diglycerol. All these methodologies permitted further scaling up.