33856-07-4

Upstream product

• 29310-88-1 3-bromoacetylcoumarin 
• 2293-07-4 1-(4-methoxyphenyl)thiourea 
• 90-02-8 salicylaldehyde 
• 3949-36-8 3-acetylcoumarin 
• 2290-65-5 trimethylsilyl isothiocyanate 
• 104-94-9 4-methoxy-aniline 
• 141099-74-3 3-(2-thiocyanatoacetyl)-2H-1-benzopyran-2-one 

Downstream Products

• 33856-15-4 5-Brom-4-(3'-cumarinyl)-2-p-methoxyphenylaminothiazol 

Relevant academic research and scientific papers

A Facile One-Step Multi-Component Approach toward the Synthesis of 3-(2-Amino-4-Thiazolyl)Coumarins by using Trimethylsilyl Isothiocyanate and their Antioxidant and Anti-Inflammatory Activity

A multi-component synthesis of 3-(2-amino-4-thiazolyl)coumarins has been reported from 3-(2-bromoacetyl)-2H-chromen-2-ones primary amines and using commercially available trimethylsilyl isothiocyanate. The structures of newly synthesized compounds were ch

An expedient one-pot tandem method for the synthesis of 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-ones under green conditions

This paper describes a facile pathway for the one-pot three-component synthesis of 3-(2-(phenylamino)thiazol-4-yl)-2H-chromen-2-ones starting from ethyl-4-chloroacetoacetate by treating it with equimolar amounts of various phenylthioureas independently re

PEG-600 mediated one-pot reaction of 3-acetyl-2: H -chromen-2-one with heterylthiols and phenylthioureas using tetrabutylammonium tribromide as an efficient green reagent

A simple method for the one-pot reaction of 3-acetyl-2H-chromen-2-one with different heterylthiols and phenylthioureas under green conditions using tetrabutylammonium tribromide (TBATB) as an efficient reagent has been described. 3-Acetyl-2H-chromen-2-one

A two-component protocol for synthesis of 3-(2-(substituted phenylamino)thiazol-4-yl)-2H-chromen-2-ones

An efcient 2-component synthesis of a series of 3-(2-(substituted phenylamino)thiazol-4-yl)-2H-chromen-2- ones (3a-j) was achieved by the reaction of 3-(2-thiocyanatoacetyl)-2H-chromen-2-one (1) with a variety of suitably substituted anilines in 1:1 molar ratio in ethanol. The structures of the products were established by elemental analyses, and UV-vis, FTIR, 1H and 13C NMR, and mass spectroscopy. 3-(2-(4-Methylphenylamino)thiazol-4-yl)-2H-chromen- 2- one (3j) was further characterized by single crystal X-ray diffraction study. This compound, C19H14N2 OS, crystallizes in the orthorhombic space group Pna21, with Z = 4, and unit cell parameters a = 13.0785(11), b = 25.746(2), c = 4.7235(3) A, α=β=γ= 90°. TUeBITAK.