33858-35-4

Usage

Heterocyclic aromatic compound

Indole ring The compound contains an indole ring, which is a five-membered ring with one nitrogen atom and four carbon atoms, making it a heterocyclic aromatic compound.

Ethyl ester derivative

Ester functional group The compound is an ethyl ester derivative of 1H-indole-2-carboxylic acid, meaning it has an ester functional group (-COO-) attached to an ethyl group (-CH2CH3).

Organic synthesis

Synthesis applications 1H-Indole-2-carboxylic acid, 4-amino-, ethyl ester (9CI) is commonly used in organic synthesis, indicating its versatility in creating various chemical compounds.

Pharmaceutical research

Potential drug development Due to its structural properties and functional groups, the compound may have potential applications in the development of new drugs or therapeutics, making it of interest in pharmaceutical research.

Upstream product

• 4993-93-5 4-nitro-1H-indole-2-carboxylic acid ethyl ester 

Downstream Products

• 220677-63-4 ethyl N-(3,4-dichlorobenzyl)-4-aminoindole-2-carboxylate 
• 112089-66-4 5-(benzylamino)-1H-indole-2-carboxylic acid 
• 104713-40-8 2-({5-[(1H-indol-2-ylcarbonyl)amino]-1H-indol-2-yl}carbonyl)-1,2,8,8a-tetrahydro-7-methylcyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one 
• 101151-43-3 [2-(5-Benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-urea 
• 112089-95-9 Methanesulfonic acid 5-benzyloxy-8-methyl-3-(5-ureido-1H-indole-2-carbonyl)-1,2,3,6-tetrahydro-pyrrolo[3,2-e]indol-1-ylmethyl ester 
• 112243-84-2 5-(benzyloxy)-1,2,3,6-tetrahydro-8-methyl-3-<<5-<(1H-indol-2-ylcabonyl)amino>-1H-indol-2-yl>carbonyl>benzo<1,2-b:4,3-b'>dipyrrole-1-methanol 
• 112243-85-3 Methanesulfonic acid 5-benzyloxy-3-{4-[(1H-indole-2-carbonyl)-amino]-1H-indole-2-carbonyl}-8-methyl-1,2,3,6-tetrahydro-pyrrolo[3,2-e]indol-1-ylmethyl ester 
• 110314-42-6 5-<(1H-benzofuran-2-ylcarbonyl)amino>-1H-indole-2-carboxylic acid 
• 112089-67-5 ethyl 5-(benzylamino)-1H-indole-2-carboxylate 

Relevant academic research and scientific papers

COMPOUNDS AND METHODS FOR ENHANCING INNATE IMMUNE RESPONSES

Provided are certain compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections.

Monocyte chemoattractant protein-1 inhibitor compounds

The invention concerns the use of a compound of the formula (I) in which Z, X, T, A, R1, R2, p and q have any of the meanings defined herein, and their pharmaceutically acceptable salts or in vivo hydrolysable esters, in the treatment of a disease or condition mediated by monocyte chemoattractant protein-1 (MCP-1). Certain of the components of formula (I) are novel and are provided, together with pharmaceutical compositions thereof, as further features of the invention.

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065

The synthesis, physicochemical properties, and biological activities of a series of novel spiro cyclopropyl compounds, modeled on the potent antitumor antibiotic CC-1065 (1), are described. Many of these synthetic analogues are significantly more effectiv

Synthesis of Isomeric Benzodipyrroles

Ethyl aminoindole-2-carboxylates (2), obtained by catalytic reduction of ethyl nitroindole-2-carboxylates (1) using Raney nickel, when subjected to Japp-Klingemann reaction furnish the respective indolylhydrazones (3).The latter undergo cyclization with H2SO4 to yield different isomeric benzodipyrroles (4-6).