33861-07-3

Upstream product

• 7252-83-7 1-bromo-2,2-dimethoxyethane 
• 108-38-3 m-xylene 
• 34589-46-3 (2,4-dimethylphenyl)magnesium bromide 
• 89-74-7 2,4-dimethylacetophenone. 
• 71-55-6 1,1,1-trichloroethane 
• 3478-88-4 2,2',4,4'-tetramethylbenzophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 10224-95-0 1,1-bis-(2,4-dimethyl-phenyl)-ethane 
• 33674-66-7 Bis-<2,2-(2,4-dimethylphenyl)vinyl>selenid 

Relevant academic research and scientific papers

Enantioselective Radical-Polar Crossover Reactions of Indanonecarboxamides with Alkenes

Highly efficient asymmetric intermolecular radical-polar crossover reactions were realized by combining a chiral N,N′-dioxide/NiII complex catalyst with Ag2O under mild reaction conditions. Various terminal alkenes and indanonecarboxamides/esters underwent radical addition/cyclization reactions to afford spiro-iminolactones and spirolactones with good to excellent yields (up to 99 %) and enantioselectivities (up to 97 % ee). Furthermore, a range of different radical-mediated oxidation/elimination or epoxide ring-opening products were obtained under mild reaction conditions. The Lewis acid catalysts exhibited excellent performance and precluded the strong background reaction.

Metal-free Mizoroki-Heck type reaction: A radical oxidative coupling reaction of 2-chloro-dithiane with substituted olefins

An efficient metal-free Mizoroki-Heck type reaction of di- and tri-substituted alkenes with 2-chloro-dithiane has been developed under ambient pressure of air or using a relatively low loading of BF3·Et2O. This study represents a new environmentally friendly method for the syntheses of dithianyl-substituted alkene derivatives via a radical oxidative coupling process.