33867-36-6

Basic information

• Product Name: 5-Oxaspiro[2.4]heptan-6-one
• Synonyms: 5-Oxaspiro[2.4]heptan-6-one
• CAS NO: 33867-36-6
• Molecular Formula: C6H8O2
• Molecular Weight: 112.12652
• Mol File: 33867-36-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 232℃
• Flash Point: 88℃
• Appearance: /
• Density: 1.19
• CAS DataBase Reference: 5-Oxaspiro[2.4]heptan-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Oxaspiro[2.4]heptan-6-one(33867-36-6)
• EPA Substance Registry System: 5-Oxaspiro[2.4]heptan-6-one(33867-36-6)

Safety Data

• Hazardous Substances Data: 33867-36-6(Hazardous Substances Data)

Usage

General Description

5-Oxaspiro[2.4]heptan-6-one, also known as 1,6-dioxaspiro[4.4]nonane, is a cyclic organic compound with a unique spiro ring structure. It is commonly used as a building block for the synthesis of various pharmaceuticals and biologically active compounds. This chemical is also used as a flavoring agent in the food industry and as a fragrance ingredient in the production of perfumes. 5-Oxaspiro[2.4]heptan-6-one has a wide range of applications due to its versatile chemical properties and is of significant interest in the fields of chemistry, pharmaceuticals, and fragrance production.

Upstream product

• 157-46-0 2-Oxa-spiro<3,2>hexan 
• 201230-82-2 carbon monoxide 
• 7440-66-6 zinc 

Downstream Products

• 142148-13-8 1-hydroxymethylcyclopropylacetic acid methyl ester 

Relevant articles and documents

Efficient Synthesis of γ-Lactones by Cobalt-Catalyzed Carbonylative Ring Expansion of Oxetanes under Syngas Atmosphere

A practical route from oxetane or thietane to γ-(thio)butyrolactone via solvated-proton-assisted cobalt-catalyzed carbonylative ring expansion under syngas atmosphere has been established. A wide variety of γ-(thio)butyrolactones can be afforded in good to excellent yields. The versatility of this method has been well demonstrated in the synthesis of intermediates towards the natural product Arctigenin as well as the pharmaceuticals Baclofen and Montelukast. The observed promoting effect of glycol ether solvent has been rationally interpreted.

NOVEL HIV REVERSE TRANSCRIPTASE INHIBITORS

The invention is related to compounds of Formula (I) or a pharmaceutically acceptable salt, solvate, ester, and/ or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.