338744-54-0Relevant academic research and scientific papers
A highly convergent synthesis of a hexasaccharide derived from the oligosaccharide of group B type III Streptococcus
Demchenko, Alexei,Boons, Geert-Jan
, p. 1629 - 1632 (1997)
We have developed a novel glycosylation strategy which enabled a highly convergent assembly of a hexasaccharide derived from group B type III Streptococcus.
A highly convergent synthesis of a complex oligosaccharide derived from group B type III Streptococcus
Demchenko,Boons
, p. 2547 - 2554 (2007/10/03)
An efficient synthesis of a heptasaccharide derived from group B type III Streptococcus carrying an artificial spacer (1) is described. Rapid assembly of a protected heptasaccharide (16a) is accomplished from readily available building blocks 2-5 without a single protecting group manipulation between glycosylation steps. The synthetic strategy may be applied to the assembly of other branched complex oligosaccharides. The deprotected heptasaccharide 1 was coupled to a poly[N-(acryloyloxy)succinimide, and the resulting material will be used for the development of an ELISA assay to detect antibodies against GBS, type III in pregnant women.
