33875-34-2

Basic information

• Product Name: (R)-2-Cyano-2-phenyl-butyryl chloride
• CAS NO: 33875-34-2
• Molecular Weight: 207.659
• Mol File: 33875-34-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-Cyano-2-phenyl-butyryl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Cyano-2-phenyl-butyryl chloride(33875-34-2)
• EPA Substance Registry System: (R)-2-Cyano-2-phenyl-butyryl chloride(33875-34-2)

Safety Data

• Hazardous Substances Data: 33875-34-2(Hazardous Substances Data)

Upstream product

• 171038-14-5 (2R)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 2-cyano-2-phenylbutanoate 
• 24150-19-4 (R)-2-Cyano-2-phenyl-butyric acid 
• 24150-19-4 2-Cyano-2-phenyl-butyric acid 
• 24150-22-9 (S)-(+)-2-Phenyl-2-cyano-buttersaeure 
• 769-68-6 2-phenylbutanenitrile 
• 718-71-8 ethyl 2-cyano-2-phenylbutanoate 
• 24150-19-4 2-cyano-2-phenylbutanoic acid 
• 24130-91-4 2-Aethyl-2-phenylmalonsaeuremonoamid 

Downstream Products

• 33875-36-4 2-Isocyanato-2-phenyl-butyronitrile 
• 33875-36-4 2-Isocyanato-2-phenyl-butyronitrile 
• 1357283-25-0 meso-2,4-diethyl-3-oxo-2,4-diphenylpentanedinitrile 
• 26333-37-9 meso-2,3-Diethyl-2,3-diphenylsuccinodinitril 
• 80544-77-0 2-cyano-2-ethyl-2-phenylacetic acid morpholide 
• 75356-38-6 racem-α-Aethyl-α-cyan-benzylisocyanat 

Relevant articles and documents

The synthesis and stereospecific solid-state photodecarbonylation of hexasubstituted meso- and d,l-ketones

Tertiary carbanions were trapped with half an equivalent of diphosgene to give meso- and d,l-hexasubstituted ketones in moderate yields and modest diastereoselectivities. The ketones were also synthesized by a step-wise synthesis in which the carbonyl group was first installed as an acid before activation and the second nucleophilic attack. This second method gave lower yields but similar diastereoselectivites. Steric limits of both methods were also determined. The photolysis of the resulting crystalline ketones gave a mixture of products in solution, but took place chemoselectively and diastereospecifically in the solid-state. The Royal Society of Chemistry and Owner Societies.

Racemic and Optically Active Hydantoins from Disubstituted Cyanoacetic Acids

Starting from the chiral disubstituted cyanoacetic acids 1 the racemates and some enantiomers of the 5,5-disubstituted hydantoins 6 and of the 3-methylhydantoins 7 are synthesized via the isocyanates 3.Their absolute configurations are determined.