33876-19-6

Upstream product

• 237765-29-6 benzyl (S)-[1-(hydroxyimino)-4-methylpentan-2-yl]carbamate 

Downstream Products

• 124511-22-4 5-<1-(S)-(benzyloxycarbonylamino)-3-methylbutyl>-1-tetrazolyl acetic acid methyl ester 
• 124453-39-0 5-<1-(S)-(benzyloxycarbonylamino)-3-methylbutyl>-2-tetrazolyl acetic acid methyl ester 
• 124453-42-5 5-<1-(S)-(benzyloxycarbonyl-L-prolylamino)-3-methylbutyl>-1-tetrazolylacetamide 
• 124453-40-3 5-<1-(S)-(benzyloxycarbonylamino)-3-methylbutyl>-1-tetrazolylacetamide 
• 124453-41-4 5-<1-(S)-(benzyloxycarbonylamino)-3-methylbutyl>-2-tetrazolylacetamide 
• 124453-38-9 5-<1-(S)-(L-prolylamino)-3-methylbutyl>-1-tetrazolylacetamide 

Relevant academic research and scientific papers

A Practical Synthesis of 5-Substituted 1 H -Tetrazoles from Aldoximes Employing the Azide Anion from Diphenyl Phosphorazidate

5-Substituted 1 H -tetrazoles were effectively synthesized from aldoximes and diphenyl phosphorazidate (DPPA) under reflux conditions in xylenes. Various aldoximes underwent the cycloaddition reaction to afford the corresponding 5-substituted 1 H -tetrazoles in short reaction times and in good yields. Chiral aldoximes derived from amino acids also gave aminotetrazoles with almost no racemization.