33878-63-6

Basic information

• Product Name: 2-methyl-1-(1H-tetrazol-5-yl)butan-1-amine hydrochloride
• CAS NO: 33878-63-6
• Molecular Weight: 191.664
• Mol File: 33878-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-1-(1H-tetrazol-5-yl)butan-1-amine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1-(1H-tetrazol-5-yl)butan-1-amine hydrochloride(33878-63-6)
• EPA Substance Registry System: 2-methyl-1-(1H-tetrazol-5-yl)butan-1-amine hydrochloride(33878-63-6)

Safety Data

• Hazardous Substances Data: 33878-63-6(Hazardous Substances Data)

Relevant articles and documents

α-Amino Acid-Isosteric α-Amino Tetrazoles

The synthesis of all 20 common natural proteinogenic and 4 otherα-amino acid-isosteric α-amino tetrazoles has been accomplished, whereby the carboxyl group is replaced by the isosteric 5-tetrazolyl group. The short process involves the use of the key Ugi tetrazole reaction followed by deprotection chemistries. The tetrazole group is bioisosteric to the carboxylic acid and is widely used in medicinal chemistry and drug design. Surprisingly, several of the common α-amino acid-isosteric α-amino tetrazoles are unknown up to now. Therefore a rapid synthetic access to this compound class and non-natural derivatives is of high interest to advance the field.