3389-74-0Relevant academic research and scientific papers
ASYMMETRIC HYDROGENATION OF ENOL PHOSPHINATES CATALYZED BY A CHIRAL FERROCENYLPHOSPHINE- RHODIUM COMPLEX. ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE SECONDARY ALKYL ALCOHOLS
Hayashi, Tamio,Kanehira, Koichi,Kumada, Makoto
, p. 4417 - 4420 (2007/10/02)
Catalytic asymmetric synthesis of secondary alkyl alcohols (up to 78 percent ee) was accomplished by asymmetric hydrogenation of enol diphenylphosphinates, derived from prochiral ketones such as acetophenone, 3-methyl-2-butanone, and 2-octanone, in the presence of a cationic rhodium complex of (R)-1-ethanol (BPPFOH).
