338974-75-7Relevant academic research and scientific papers
Synthetic analogues of SB-219383. Novel C-glycosyl peptides as inhibitors of tyrosyl tRNA synthetase
Brown, Pamela,Eggleston, Drake S.,Haltiwanger,Jarvest, Richard L.,Mensah, Lucy,O'Hanlon, Peter J.,Pope, Andrew J.
, p. 711 - 714 (2001)
Novel inhibitors of bacterial tyrosyl tRNA synthetase have been synthesised in which the cyclic hydroxylamine moiety of SB-219383 is replaced by C-pyranosyl derivatives. Potent and selective inhibition of bacterial tyrosyl tRNA synthetase was obtained.
